Gene Expression And Metabonomic Profilings In P53+/- Knockout Mice Following Diethylstilbestrol Treatment

Clastogenic carcinogen diethylstilbestrol (DES) results in a broad of spectrum of toxic and carcinogenic effects in humans and rodents. Female C57BL/6J wild-type mice (23-25g) and female p53 +/1- hemizygous mice were treated with DES (500 umol/kg) i .p., once daily for 4 days. Control animals wer...

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Détails bibliographiques
Auteur principal: Salleh, Mohd Nazil
Format: Thèse
Langue:anglais
anglais
Publié: 2003
Accès en ligne:http://psasir.upm.edu.my/id/eprint/11274/1/FPSK_P_2003_2.pdf