Immunomodulatory action of new curcumin analogue [2,6-BIS(2,5-dimethoxybenzylidene) cyclohexanone] on major inflammatory mediator expression in activated macrophage and synovial fibroblast cells

Rheumatoid arthritis is a chronic inflammatory disease characterized by abnormal immune phenomena involving macrophage and synovial fibroblast resulting in progressive joints destruction. In this study, a series of newly synthesized curcumin diarylpentanoids were screened for their anti-inflammatory...

Description complète

Détails bibliographiques
Auteur principal:	Lee, Ka Heng
Format:	Thèse
Langue:	anglais
Publié:	2012
Sujets:	Cyclohexanones Fibroblasts Macrophages
Accès en ligne:	http://psasir.upm.edu.my/id/eprint/39202/1/FBSB%202012%2034R.pdf

Documents similaires

Antinociceptive profile of a synthetic curcuminoid derivative, 2,6-bis-4-(hydroxy-3-methoxy-benzilidine)-cyclohexanone in murine model of induced-nociception
par: Lee, Ming Tatt
Publié: (2013)

The Synthesis and Bioactivity of 2,6-Bisbenzylidenecyclohexanone, Pyrazoline, Chalcone and Oxadiazole Derivatives and Computational Studies on Some of These Compounds
par: Lam, Kok Wai
Publié: (2010)

Antibacterial and antioxidant activities of Piper cubeba L. berries extract and its cytotoxicity effect on 3T3 human fibroblast and HEPG2 cell lines
par: Lou, Shuai Qiang
Publié: (2021)

Toxicity effects of curcumin analogue, 2, 6-BIS (2-fluorobenzylidene) cyclohexanone on zebrafish (Danio rerio F. Hamilton, 1822)
par: Nazarudin, Nur Amiza
Publié: (2017)

Construction of recombinant newcastle disease virus expressing granulocyte-macrophage colony-stimulating factor
par: Fikri Ooi, Nur Zafirah
Publié: (2022)

Drug repurposing of clinically-approved drugs to target epithelial-mesenchymal transition using in silico analysis
par: Ong, Chun Hao
Publié: (2021)

Anti-invasive effects of 2,6-bis-(4-hydroxyl-3methoxybenzylidine) cyclohexanone and its molecular targets associated with invadopodia formation in MDA-MB-231 human breast cancer cells
par: Harun, Siti Nor Aini
Publié: (2018)

Prediction and expression of microrna targeting interleukin-17a in chondrocytes and synovial fibroblasts isolated from osteoarthritic knee
par: Ng Jun, Quan
Publié: (2023)

Immunomodulatory Activity Of Mannheimia Haemolytica A2 Lipopolysaccharide
par: Mohd.Salim, Azlina
Publié: (2003)

Regulation Of Macrophage Cellular Response By Clinacanthus Nutans Extracts In J774.2 Macrophage Cell Line
par: Mohamed, Nur Mazidah Haji Noor
Publié: (2019)

Immunomodulatory effects of asiatic acid and madecassoside of centella asiatica (pegaga) on j774a.1 mouse macrophage cell line
par: Harun, Nurul Hikmah
Publié: (2020)

Cytotoxic and apoptotic effects of curcumin and thymoquinone on HSC-2 cell line
par: Saleem, Khadeeja
Publié: (2021)

Characterization Of Biomechanical Properties Of Articular Cartilage Across Synovial Joint
par: Jaafar, Yusra Liyana
Publié: (2017)

Toxicity, permeability and drug-metabolizing enzyme activities of curcumin analogues
par: Yakubu, Ndatsu
Publié: (2015)

Evaluation of curcumin derivatives as new cyclooxygenase-2 inhibitors via in silico and in vitro analyses
par: Abdul Bahari, Mohammad Nazri
Publié: (2016)

Biotransformation Of Cis/Trans 3,7-Dimethyl-2,6-Octadien-1-Ol Mediated By Saccharomyces Cerevisiae
par: Khor, Guat Kheng
Publié: (2011)

Differential pulse anodic stripping voltammetry of cadmium, copper, lead and zinc in the presence of N,N’-bis[2-hydroxyacetophenone]ethylenediamine
par: Mohd. Yusof, Nur Yasarah
Publié: (2014)

Copper-based catalysts supported on nitrogen-doped reduced graphite oxide for dehydrogenation of cyclohexanol to cyclohexanone
par: Mageed, Alyaa Khadhier
Publié: (2017)

Controlled-release of curcumin from poly(lactide-co-glycolide) acid/albumin/curcumin and silica/albumin/curcumin drug-delivery systems
par: Pondi, Shafiyah
Publié: (2017)

A selective copper(ii) electrode based on 2-acetylpyridine -(1r)-(-)-fenchone azine ligand and 2,6-diacetylpyridine -dj....(1id-(-}-fenchone diazine ligand
par: Mohamad Idris Saidin
Publié: (2014)

Integration of polypyrrole with metal complexes of 2,6-pyridinedicarboxylic acid and their electrochemical studies as potential electrode material in supercapacitor application / Sadia Tanzim
par: Sadia , Tanzim
Publié: (2023)

Polyvinyl alcohol-grafted-multiwalled carbon nanotubes as a delivery system for curcumin in H2O2-induced damaged neuroblastoma SH-SY5Y cells
par: Ahmad Zawawi, Nurliyana
Publié: (2017)

Articular cartilage morphology and synovial fluid protein biomarkers in the monosodium iodoacetate-induced osteoarthritis rabbit model
par: Tan, Wei Miao @ Rachel
Publié: (2017)

Biosynthesis Of Endosome-Specific Lipid Bis(Monoacylglycero)Phosphate
par: Lim,, Shi Rou
Publié: (2018)

The effect of vitamin e on basic fibroblast growth factor level in human fibroblast cell culture
par: Shaw Altul Akbma, Harun Nor Rashid
Publié: (2007)

The Effects Of Mitragynine From Mitragyna Speciosa On The Mrna Expression Of Cox-1 And Cox-2 In Lipopolysaccharide-Stimulated Raw264.7 Macrophage Cells
par: Utar, Zulkhurnain
Publié: (2014)

The Effects Of Mitragynine From Mitragyna Speciosa On The Mrna Expression Of Cox-1 And Cox-2 In Lipopolysaccharide-Stimulated Raw264.7 Macrophage Cells
par: Utar, Zulkhurnain
Publié: (2014)

Analysis Of Immunological Responses Of Murine Macrophages To Hydroxyapatite
par: Gopinath, Vellore Kannan
Publié: (2006)

Studies On Prospect Of Curcumin As An Analytical Reagent For Aluminium.
par: Zhu, Qing Gong
Publié: (2009)

Analysis Of Immunological Responses Of Murine Macrophages To Hydroxyapatite
par: Gopinath, Vellore Kannan
Publié: (2006)

Spin-crossover and mesogenic properties of cobalt(ii) and iron(ii) complexes with ligands derived from 2,6-pyridinedicarboxaldehyde and 1-aminoalkanes / Nur Linahafizza Mohd Noor
par: Mohd Noor, Nur Linahafizza
Publié: (2015)

In vitro plant regenaration of tobacco (nicotiana tabaccum TAPM 26)
par: Kaya, Yilmaz
Publié: (2010)

Screening Of Malaysian Medicinal Plants For Immunomodulatory And Haemolytic Activities
par: Samat, Nor Azura
Publié: (2003)

Immunomodulatory and cell cycle regulatory effects of clinacanthus nutans
par: Ghazali, Wan Afiqah Syahirah Wan @ Wan Azmi
Publié: (2018)

Application of Comparative Genomic Hybridization and Fluorescent in Situ Hybridization Techniques on Human Glioma Cell Lines Treated with Bis[S-Methyl-A-N-(2 - Furylmethylketone) Dithiocarbazato] Cadmium(Ii)
par: Abu Bakar, Suhaili
Publié: (2004)

Effect of fibroblast and platelet-derived growth factors on co-culture of human gingival fibroblasts and umbilical vein endothelial cells
par: Allah, Nasar Um Min
Publié: (2018)

Edible Bird's Nest treatment effects on subchondral bone and articular cartilage changes and synovial fluid proteome profiles in an osteoarthritis rabbit model
par: Syed Sulaiman, Sharifah Zakiah
Publié: (2022)

The determination of agreement between Transducer-Like Enhancer split-1 (TLE-1) and Fluorescence In Situ Hybridization (FISH) in synovial sarcoma cases
par: Salehan, Noraziah
Publié: (2018)

Immunomodulatory Effects of Human Mesenchymal Stem Cells on Neutrophil Functions
par: Maqbool, Maryam
Publié: (2011)

Synthesis, characterization and antioxidant activities of ni(ii) cu(ii), and zn(ii) complexes of substituted 4-phenyl-1,3,5-triazine-2,6- salicylaldimine / Abdulaziz Ali Alomari
par: Alomari, Abdulaziz Ali
Publié: (2012)