RNA interference silencing of interleukin-6 in mesenchymal stromal cells and antitumour efficacy against multiple myeloma cells

Studies demonstrated that mesenchymal stromal cells (MSC) from bone marrow (BM) stroma produced high concentrations of interleukin-6 (IL-6) that promoted multiple myeloma growth. In view of the failure of IL-6 monoclonal antibody therapy to demonstrate substantial clinical responses in early clinica...

詳細記述

書誌詳細

第一著者:	Teoh, Hoon Koon
フォーマット:	学位論文
言語:	英語
出版事項:	2015
主題:	RNA Interference - physiology RNAi Therapeutics - instrumentation Multiple Myeloma - microbiology
オンライン･アクセス:	http://psasir.upm.edu.my/id/eprint/64839/1/FPSK%28p%29%202015%2024.pdf