Design, synthesis, and biochemical assay of peptide inhibitors derived from α-enolase for use against peptidylarginine deiminase type 4

Rheumatoid arthritis (RA) is an inflammatory autoimmune disease affecting about 0.5–1.0% of the world population. Peptidylarginine deiminase type 4 (PAD4) is a responsible protein for the occurrence of RA by catalyzing citrullination of proteins. The citrullinated proteins act as autoantigens by sti...

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Détails bibliographiques
Auteur principal:	Ahmad Nadzirin, Izzuddin
Format:	Thèse
Langue:	anglais
Publié:	2013
Sujets:	Arthritis Peptides - Synthesis
Accès en ligne:	http://psasir.upm.edu.my/id/eprint/67427/1/FS%202013%2059%20IR.pdf

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