Design, synthesis, and biochemical assay of peptide inhibitors derived from α-enolase for use against peptidylarginine deiminase type 4
Rheumatoid arthritis (RA) is an inflammatory autoimmune disease affecting about 0.5–1.0% of the world population. Peptidylarginine deiminase type 4 (PAD4) is a responsible protein for the occurrence of RA by catalyzing citrullination of proteins. The citrullinated proteins act as autoantigens by sti...
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| 格式: | Thesis |
| 语言: | 英语 |
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2013
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| 在线阅读: | http://psasir.upm.edu.my/id/eprint/67427/1/FS%202013%2059%20IR.pdf |