Cytotoxicity of SRJ23 and its derivatives, expression and SRJ23 binding of KRas G12V oncoprotein
Oncogenic KRas signaling is often associated with a poor prognosis of pancreatic cancer. Effort to target oncogenic KRas signaling persists for years but without much success due to its „undruggable‟ property. In recent years, several small-molecule KRas inhibitors such as SRJ23 were developed to in...
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| 格式: | Thesis |
| 语言: | 英语 |
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2017
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| 在线阅读: | http://psasir.upm.edu.my/id/eprint/68578/1/FPSK%28M%29%202018%2013.pdf |