Evaluation of curcumin derivatives as new cyclooxygenase-2 inhibitors via in silico and in vitro analyses

Prostaglandin E2 (PGE2) is one of the lipid mediators of inflammation. Chronic inflammation drives overproduction of PGE2 that leads to development of chronic inflammatory diseases. PGE2 is synthesized by cyclooxygenase (COX) enzyme that exists in isoforms of COX-1, which is constitutively expressed...

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Détails bibliographiques
Auteur principal:	Abdul Bahari, Mohammad Nazri
Format:	Thèse
Langue:	anglais
Publié:	2016
Sujets:	Turmeric - Therapeutic use Cyclooxygenase 2 - Inhibitors Chemical analysis
Accès en ligne:	http://psasir.upm.edu.my/id/eprint/68964/7/FBSB%202016%207%20-%20IR%20edit.pdf

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