Evaluation of curcumin derivatives as new cyclooxygenase-2 inhibitors via in silico and in vitro analyses

Prostaglandin E2 (PGE2) is one of the lipid mediators of inflammation. Chronic inflammation drives overproduction of PGE2 that leads to development of chronic inflammatory diseases. PGE2 is synthesized by cyclooxygenase (COX) enzyme that exists in isoforms of COX-1, which is constitutively expressed...

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主要作者:	Abdul Bahari, Mohammad Nazri
格式:	Thesis
语言:	英语
出版:	2016
主题:	Turmeric - Therapeutic use Cyclooxygenase 2 - Inhibitors Chemical analysis
在线阅读:	http://psasir.upm.edu.my/id/eprint/68964/7/FBSB%202016%207%20-%20IR%20edit.pdf