Establishment and validation of a monoclonal cell-based reporter assay for screening of hypoxia-inducible factor activities
Cell-based assay is a powerful tool in the fields of drug discovery. One of the main targets of current drug development is transcription factor. Hypoxia-inducible factors (HIFs) are transcription factors, which involve in cellular oxygen homeostasis and association with disease pathophysiology. Hen...
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| Format: | Thèse |
| Langue: | anglais |
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2017
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| Accès en ligne: | http://psasir.upm.edu.my/id/eprint/70154/1/FBSB%202017%209%20-%20IR.pdf |