Screening, design, synthesis and bioactivity of inhibitors against Protein Arginine Deiminase type IV
Protein Arginine Deiminase IV (PAD4) is a new target for rheumatoid arthritis (RA) therapeutic. It catalyses the citrullination process in human body that produces citrullinated protein which is believed to be the root cause of RA. Inhibitor for the enzyme can be a drug for the treatment of RA. The...
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| Format: | Thèse |
| Langue: | anglais |
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2015
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| Accès en ligne: | http://psasir.upm.edu.my/id/eprint/71185/1/FS%202015%2072%20IR%28155%29edited.pdf |