Structural and biophysical characterisations of MeCP2 MBD mutants that correlate with Rett syndrome
Methyl-CpG binding protein (MBD) family consists of Methyl-CpG Binding Protein 2 (MeCP2), Methyl-CpG Binding Domain Protein 1 (MBD1), MBD2, MBD3 and MBD4 where MeCP2 is the prototype of the family. MeCP2 contains several domains: (a) a methyl-CpG binding domain (MBD), (b) a transcriptional repressio...
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| Format: | Thèse |
| Langue: | anglais |
| Publié: |
2016
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| Accès en ligne: | http://psasir.upm.edu.my/id/eprint/75351/1/FPSK%28M%29%202016%2047.pdf |