| الملخص: | Cone beam computed tomography (CBCT) system is a broadly used imaging modality
in dentistry nowadays. It allows the imaging of high contrast structures of the oral
region at a high resolution. The effect of CBCT scan parameters on trabecular bone
microstructure (Tb.N), (Tb.Th), (Tb.Sp), and (BV/TV) has been studied, while the
effect of CBCT reconstruction parameters is still lacking. Five sectioned maxillae of
adult Dorper male sheep (age ranging from 20-48 months and body weight 50-60 kg)
were scanned using a CBCT system (Carestream 9000, Kodak) and a Micro-CT (μCT)
system (SkyScan 1076, Kontich, Belgium). In the first part of this study, the images for
μCT and CBCT were processed and analyzed to study the reliability of CBCT
trabecular bone microstructure assessment in comparison with Micro-CT. In the second
part of this study, the effect of CBCT reconstruction parameters (reconstruction voxel
size, threshold value, and the size and content of the region of interest) on trabecular
bone microstructure assessment were evaluated. The statistical analysis showed that
CBCT is reliable for the trabecular microstructure measurement in comparison with
μCT. For the reconstruction voxel size, there was no significant difference between
different reconstruction voxel sizes (76, 100, and 200 μm3
). For the threshold value, an
increase and decrease in the chosen optimal value by 15% was done. Decreasing the
chosen optimal value (by 15%) showed significant difference on all trabecular bone
parameters, whereas increasing the value had no significant effect. Lastly, the region of
interest (Group 1, ROI that only contained trabecular bone, Group 2, ROI contained
cortical bone and trabecular bone) showed the inclusion of cortical bone in the ROI
showed significant difference on the Tb.Th and BV/TV measurements. In conclusion,
BONE MICROSTRUCTURE ASSESSMENT USING CONE BEAM
COMPUTED TOMOGRAPHY DATASET
iv
CBCT (Carestream 9000, Kodak) is reliable for the trabecular bone microstructure
assessment. However, the selected CBCT reconstruction parameters can compromise
the trabecular bone microstructure measurement
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