| 要約: | Objective: To investigate the surface roughness of resin infiltrated proximal white
spot lesions (WSLs) with ICON® subjected to a pH cycling challenge and compare its
surface roughness with WSLs treated with that of Duraphat®. Materials and Methods:
Sixty extracted sound premolars were used in this in vitro study. Optical coherence
tomography (OCT) was used for baseline enamel readings and randomly divided into four
groups having fifteen specimens in each. Groups were assigned as: Sound (negative
control), Demineralised (positive control), ICON®, and Duraphat®. All specimens except
for the Sound group were subjected to an initial demineralisation in a solution containing
2.2mM calcium chloride, 2.2mM potassium meta-phosphate, and 50mM acetate buffer at
a pH of 4.5 for 7 days and enamel changes were confirmed using OCT. The Sound and
Demineralised groups acted as control while the other two groups were applied resin
infiltration (ICON®) and fluoride varnish (Duraphat®). All the specimens were measured
using a non-contact profilometer (3D Alicona) for baseline surface roughness (Ra) prior
to being subjected to a pH cycling regime for 7 days. Ra analysis was after pH cycling
was conducted and mean differences recorded. Results: Data were analysed with oneway
analysis of variance (ANOVA), and repeated measure ANOVA using SPSS (ver. 23)
at a=0.05. The Ra at baseline revealed significant differences across the group except for
the comparison of ICON® (0.314μm±0.004) to sound enamel (0.313μm±0.028). After pH
cycling the enamel surfaces treated with ICON® (0.422μm±0.004) were significantly
smoother than those treated with Duraphat® (0.583μm±0.003). After 7 days of acidic
challenge, ICON® exhibited the least change in Ra value (0.108μm). Conclusions: Within
the limitations of the study, the results showed that WSLs treated with ICON® showed
approximately the same surface roughness as sound enamel, suggesting suitability for the
treatment of WSL.
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