Isolation and identification of cyclic polyketides from Endiandra kingiana gamble (lauraceae), as BCL-XL/BAK and MCL-1/BID dual inhibitors, and approaches toward the synthesis of kingianins / Mohamad Nurul Azmi Mohamad Taib
The preliminary screening showed that the bark of Endiandra kingiana Gamble exhibited potency as a modulating agent between Bcl-xL and Bak, which prompted its chemical investigation. Two groups of compounds were isolated and characterized; the endiandric acid series and the kingianin series. Eigh...
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2015
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