Molecular sequence and structural comparison of BACE1 and BACE2 / Hoda Mirsafian
Beta-Secretase is a transmembrane aspartic protease that cleaves the amyloid precursor protein (APP) to generate amyloid beta peptide (Aβ) that is believed to be responsible for the Alzheimer’s disease (AD). Beta-Secretaes include BACE1 and BACE2 which are close homologues, sharing 61.5% similarity...
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| Format: | Thèse |
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2012
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