Virtual screening and biological assay of compound libraries for anticholinesterase activity / Sri Devi D/O Sukumaran

The current research was aimed at finding peripheral anionic site (PAS) binding acetylcholinesterase (AChE) inhibitors to be used in the treatment of Alzheimer’s disease (AD). The crystal structure of human acetylcholinesterase (hAChE) in complex with fasciculin II (2.76 Ǻ) (PDB ID: 1b41) was found...

وصف كامل

التفاصيل البيبلوغرافية
المؤلف الرئيسي: Sukumaran, Sri Devi
التنسيق: أطروحة
منشور في: 2012
الموضوعات: