p53-Mdm2 interaction targeted therapy by Nutlin-3 on nasopharyngeal carcinoma cells / Voon Yee Lin

Nutlin-3, a small-molecule inhibitor of p53-Mdm2 interaction, is known to be effective against cancers expressing wild-type (wt) p53. p53 mutations are rare in nasopharyngeal carcinoma (NPC), and hence targeting the disruption of p53-Mdm2 interaction to reactivate p53 may offer a promising therap...

Description complète

Détails bibliographiques
Auteur principal:	Voon, Yee Lin
Format:	Thèse
Publié:	2016
Sujets:	RC0254 Neoplasms. Tumors. Oncology (including Cancer)

Documents similaires

Antiproliferative, antimetastatic properties of phyllanthus specieson breastand lungcancer cell linesand their targetted signal transduction pathways / Lee Sau Har
par: Lee, Sau Har
Publié: (2013)

Enhancing human breast cancer cells destruction using combination of adenovirus P53 and hyperthermia treatment
par: Elengoe, Asita
Publié: (2015)

Combination of metformin and fec (5-fluorouracil, epirubicin, cyclophophasmide) chemotherapy as a potential therapy for targeting cancer stem cells in breast cancer / Soo Sian Siu
par: Soo , Sian Siu
Publié: (2015)

Evaluations on efficacy and immuno-stimulatory properties Tropomyosin receptor kinase C targeted peptidomimetic ligand-diiodo-boron dipyrromethene hybrids in photodynamic anticancer therapy / Kue Chin Siang
par: Kue, Chin Siang
Publié: (2016)

Expressions of P53, MDM-2 and BCL-2 and KI-67 labelling index in oral squamos cell carcinoma / Choon Yee Fan
par: Choon, Yee Fan
Publié: (2007)

Investigation of tnfr2 regulatory t cells and associated cytokines on the pathogenesis of nasopharyngeal carcinoma
par: Rahman, Engku Nur Syafirah Engku Abd
Publié: (2023)

Cellular and molecular signatures of cancer stem-like cells in hepatocellular carcinoma / Ain Zubaidah Ayob
par: Ain Zubaidah, Ayob
Publié: (2022)

Curcuma mangga-mediated synthesis of gold nanoparticles and their photothermal and protein interaction studies / Foo Yiing Yee
par: Foo , Yiing Yee
Publié: (2018)

Prevalence of palb2 germline mutations in malaysian breast cancer patients and its role in predisposition to breast cancer / Phuah Sze Yee
par: Phuah, Sze Yee
Publié: (2014)

Pattern of hmlh1, hmsh2 and hmsh6 expressions and clinical characteristics in Malaysian colorectal carcinoma cases / Khoo Joon Joon
par: Khoo, Joon Joon
Publié: (2011)

Breast conserving therapy versus mastectomy in young breast cancer patients in asian settings / Siamala Sinnadurai
par: Siamala, Sinnadurai
Publié: (2018)

Pembangunan ontologi kanser payudara bagi pemilihan data dalam meramal risiko
par: Jusoh, Fatimatufaridah
Publié: (2014)

Antitumour effect of fever range whole-body hyperthermia with curcumin in breast cancer
par: Saim, Hanim
Publié: (2020)

Hybrid watermark techniques for skin cancer images
par: Omar Adil Dheyab
Publié: (2019)

Mutable composite firefly algorithm for gene selection in microarray based cancer classification
par: Fajila, Mohamed Nisper Fathima
Publié: (2022)

Cognitive changes and their impact on functioning at work: A qualitative study on women with breast cancer / Maryam Hafsah Mohammed Selamat
par: Maryam Hafsah, Mohammed Selamat
Publié: (2016)

Depression, anxiety, and type d personality in newly diagnosed breast cancer patients: a quasi-prospective association study / Beatrice Ng Andrew
par: Beatrice, Ng Andrew
Publié: (2014)

Oncogenic role of cancer-associated fibroblast secretion in endometrial cancer progression in vitro and in vivo / Kavita S. Subramaniam
par: Kavita, S. Subramaniam
Publié: (2016)

Apoptotic and breast tumor inhibition effects of Ferulago angulata and Tanacetum polycephalum (L.) Schultz-bip / Hamed Karimian
par: Hamed , Karimian
Publié: (2017)

Immunological determinants of tuberculosis-associated immune reconstitution inflammatory syndrome (TB-IRIS) in HIV-infected patients on antiretroviral therapy / Tan Hong Yien
par: Tan, Hong Yien
Publié: (2016)

Marine algae as a source of photosensitisers for photodynamic therapy of cancer / Tang Yee Voon.
par: Tang, Yee Voon
Publié: (2010)

Evaluation of genetic alterations of IDH1, TP53 and CASP9 genes as biomarkers in glioma patients
par: Yit, Pua Jing
Publié: (2022)

Digital infrared thermography analysis for breast cancer using image textures features / Norlailah Lanisa
par: Norlailah, Lanisa
Publié: (2017)

Functional characterisation of cancer-associated fibroblasts from nasopharyngeal carcinoma / Wong Wee Lin
par: Wong, Wee Lin
Publié: (2020)

Determination of the role of miR-210 AND miR-629 in regulating response towards 1'S-1'-acetoxychavicol acetate in human cervical carcinoma cells CaSki AND SiHa / Phuah Neoh Hun
par: Phuah, Neoh Hun
Publié: (2017)

Adam-9 expression in squamous cell carcinoma, adenocarcinoma and adenosquamous cell carcinoma of the uterine cervix
par: Mohd Isa, Seoparjoo Azmel
Publié: (2012)

Developing a medical scoreboard for prediction of breast cancer recurrence / Nurul Husna Jamian
par: Jamian, Nurul Husna
Publié: (2013)

Chemical constituents and cytotoxic properties of Goniothelamus Macrophyllus / Hamidah Sahibul Anwar
par: Sahibul Anwar, Hamidah
Publié: (2008)

Development of a lectin binding assay for mucin-type O-glycosylated serum proteins: Identification of potential biomarkers for screening of breast cancer / Lee Cheng Siang
par: Lee, Cheng Siang
Publié: (2017)

An overview of breast cancer diagnostic techniques / Mohammad Mahdi Aeinehvand
par: Mohammad Mahdi , Aeinehvand
Publié: (2012)

The development of a work-directed intervention on return to work for people living with colorectal cancer / Chow Sze Loon
par: Chow, Sze Loon
Publié: (2016)

Anticancer effects of 1’s-1’- acetoxychavicol acetate and its potentiation when conjugated with human alpha fetoprotein against human tumours in Mice / Norhafiza Binti Mohd Arshad
par: Mohd Arshad, Norhafiza
Publié: (2015)

The effect of cinnamomum cassia on two breast cancer cell lines / Sima Kianpour Rad
par: Kianpour Rad, Sima
Publié: (2014)

Endoscopic ultrasound, fine needle aspiration and cytology in patiens with suspected pancreatic cancer. Emphasis on negative predictive value / Salem Omar
par: Salem , Omar
Publié: (2012)

Sexual dysfunction, body image distress and marital dissatisfaction in breast cancer patients of University Malaya Medical Centre (UMMC) / Norley Shuib
par: Norley, Shuib
Publié: (2014)

Anti-cancer effect of bix01294 towards CML cell lines / Loh Sheng Wei
par: Loh, Sheng Wei
Publié: (2016)

Symptom burden and quality of life in cam and non-cam users among breast cancer patients during chemotherapy / Chui Ping Lei
par: Chui, Ping Lei
Publié: (2015)

Characterisation and application of carbon doped aluminium oxide optically stimulated luminescence dosimeter in megavoltage photon beams for radiotherapy / Fasihah Hanum Md Yusof
par: Fasihah Hanum , Md Yusof
Publié: (2016)

A prospective evaluation of psycho-oncological factors on cancer outcomes / Caryn Chan Mei Hsien
par: Caryn, Chan Mei Hsien
Publié: (2015)

Identification of potential serum and urine biomarkers for patients with prostate cancer using lectin-based proteomic analyses / Jaime Jacqueline Jayapalan
par: Jaime Jacqueline, Jayapalan
Publié: (2015)