Drug design and synthesis of cox-2 selective inhibitors as potential NSAIDs / Abeer Abdulhadi Abdulqader
Cyclooxygenase (COX) is a key enzyme in the biosynthetic pathway leading to the formation of prostaglandins, which are mediators of inflammation. It exists mainly in two isoforms, COX-1 and COX-2. The conventional nonsteroidal anti-inflammatory drugs (NSAIDs) have gastrointestinal side effects becau...
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| Format: | Thèse |
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2016
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