Phytochemicals, essential oils and antioxidant activity from Piper ornatum N.E.Br and Piper penangense C.DC. (PIPERACEAE)

Bibliographic Details
Main Author: Nik Nur Asyiqin Nik Mohammed Ainul Azman
Format: Thesis
Language:English
Published: 2024
Subjects:
QD Chemistry
Online Access:https://ir.upsi.edu.my/detailsg.php?det=12146
Abstract Abstract here
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author Nik Nur Asyiqin Nik Mohammed Ainul Azman
author_facet Nik Nur Asyiqin Nik Mohammed Ainul Azman
author_sort Nik Nur Asyiqin Nik Mohammed Ainul Azman
description
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id upsi-12146
institution Universiti Pendidikan Sultan Idris
language English
publishDate 2024
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spelling upsi-121462025-05-29 Phytochemicals, essential oils and antioxidant activity from Piper ornatum N.E.Br and Piper penangense C.DC. (PIPERACEAE) 2024 Nik Nur Asyiqin Nik Mohammed Ainul Azman QD Chemistry <p>The purpose of the study was to investigate phytochemicals, essential oils, and</p><p>antioxidant activity from Piper ornatum N.E.Br and Piper penangense C.DC</p><p>(Piperaceae). The essential oils were obtained by hydrodistillation technique and their</p><p>compositions were evaluated by gas chromatography (GC-FID) and gas</p><p>chromatography-mass spectrometry (GC-MS). Isolation of phytochemicals was</p><p>carried out through cold extraction of the leaves followed by separation using</p><p>chromatographic techniques. The isolated compounds were confirmed by</p><p>spectroscopic data and comparison with literature. The antioxidant activity of the</p><p>essential oils, crude extracts, and phytochemicals were evaluated using the total</p><p>phenolic content (TPC) and DPPH free radical scavenging assays. The study showed</p><p>that the essential oil of P. ornatum consists of caryophyllene oxide (31.5%),</p><p>sphatulenol (5.9%), aromadendrene (4.9%), and _-caryophyllene epoxide (4.5%). The</p><p>major components of P. penangense essential oil were humulene epoxide II (31.9%),</p><p>caryophyllene oxide (9.9%), muurola-4,10(14)-dien-1-ol (9.1%), and _-ionone (8.3%).</p><p>Isolation and purification of leaves extracts from P. ornatum yielded six compounds,</p><p>namely; 5,7-dimethoxyflavone (143), 4',7-dihydroxy-3',5',5- trimethoxyflavone (285),</p><p>piperine (47), _-sitosterol (286), 4'-hydroxy-3',5',5,7-tetramethoxyflavone (287), and</p><p>3',4',5,5',7-pentamethoxyflavone (288). Three compounds were isolated from P.</p><p>penangense which are 4-allyl resorcinol (289), chavibetol (63), and dillapiole (33).</p><p>The methanolic leaf extract of P. penangense showed good antioxidant activity with</p><p>high phenolic content (360.8 mg GAE/g) and percentage inhibition of DPPH radical</p><p>scavenging (67.3%). Furthermore, 4-allyl resorcinol (289) showed the highest activity</p><p>in the DPPH assay with percentage inhibition of 51.0%. In conclusion, the essential</p><p>oils of P. ornatum and P. penangense are composed of oxygenated sesquiterpenes as</p><p>their major components. Meanwhile, phytochemical studies of both Piper species</p><p>yielded flavones, amide, sterols, and phenylpropanoids with significant antioxidant</p><p>activity. Regarding the implication of the current study, the extracts and</p><p>phytochemicals of Piper species have therapeutic potential in the prevention of free</p><p>radical-related diseases such as atherosclerosis and diabetes.</p> 2024 thesis https://ir.upsi.edu.my/detailsg.php?det=12146 https://ir.upsi.edu.my/detailsg.php?det=12146 text eng N/A openAccess Masters Perpustakaan Tuanku Bainun Fakulti Sains dan Matematik N/A
spellingShingle QD Chemistry
Nik Nur Asyiqin Nik Mohammed Ainul Azman
Phytochemicals, essential oils and antioxidant activity from Piper ornatum N.E.Br and Piper penangense C.DC. (PIPERACEAE)
thesis_level Master
title Phytochemicals, essential oils and antioxidant activity from Piper ornatum N.E.Br and Piper penangense C.DC. (PIPERACEAE)
title_full Phytochemicals, essential oils and antioxidant activity from Piper ornatum N.E.Br and Piper penangense C.DC. (PIPERACEAE)
title_fullStr Phytochemicals, essential oils and antioxidant activity from Piper ornatum N.E.Br and Piper penangense C.DC. (PIPERACEAE)
title_full_unstemmed Phytochemicals, essential oils and antioxidant activity from Piper ornatum N.E.Br and Piper penangense C.DC. (PIPERACEAE)
title_short Phytochemicals, essential oils and antioxidant activity from Piper ornatum N.E.Br and Piper penangense C.DC. (PIPERACEAE)
title_sort phytochemicals essential oils and antioxidant activity from piper ornatum n e br and piper penangense c dc piperaceae
topic QD Chemistry
url https://ir.upsi.edu.my/detailsg.php?det=12146
work_keys_str_mv AT niknurasyiqinnikmohammedainulazman phytochemicalsessentialoilsandantioxidantactivityfrompiperornatumnebrandpiperpenangensecdcpiperaceae

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