| _version_ |
1855626363878244352
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| author |
Norzafneza Mohd Arriffin
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| author_facet |
Norzafneza Mohd Arriffin
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| author_sort |
Norzafneza Mohd Arriffin
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| description |
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| format |
Thesis
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| id |
upsi-13225
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| institution |
Universiti Pendidikan Sultan Idris
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| language |
English
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| publishDate |
2012
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| record_format |
sWADAH
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| record_pdf |
Restricted
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| spelling |
upsi-132252025-08-25 Chemical constituents of Malaysian Aquilaria crassna Pierre (gaharu) 2012 Norzafneza Mohd Arriffin <p>Studies of Aquilaria crassna Pierre from the leaves and barks had been divided into four parts;</p><p>phytochemical screening, essential oils, chemical constituents and antimicrobial activities.</p><p>Samples were extracted using three solvents; hexane, dichloromethane and methanol. All</p><p>six extracts; three leaves and three barks had underwent phytochemical screening to detect</p><p>the presence of secondary metabolites. Fresh samples of leaves and barks went through</p><p>hydrodistillation process using Dean Stark apparatus to obtain essential oil. Isolation of</p><p>chemical compounds had been done using several chromatography techniques such as column</p><p>chromatography (CC), preparative thin layer chromatography (PTLC) and monitoring with thin</p><p>layer chromatography (TLC). Totally, seven pure compounds successively isolated. Four pure</p><p>compounds isolated from leaves; 5-hydroxy- 7,4 -dimethoxyflavone (29) and epifriedelanol</p><p>(30) from hexane extract while squalene (31) and 5-hydroxy-7,4 - dimethoxyflavone (29)</p><p>from dichloromethane extract. Further extraction on barks yield three pure compounds; </p><p>sec-nonacosyl ester (32), 5-hydroxy-7,4 - dimethoxytlavone (29) and bis (2-ethylhexyl)</p><p>phthalate (33). Finally, crude extracts had been screened for antimicrobial activities towards four</p><p>bacteria. Results show that Staphylococcus aureus was the most susceptible bacteria to all six</p><p>extracts. Whilst, the least susceptible strain was Pseudomonas aeruginosa.</p><p></p> 2012 thesis https://ir.upsi.edu.my/detailsg.php?det=13225 https://ir.upsi.edu.my/detailsg.php?det=13225 text eng N/A openAccess Masters Perpustakaan Tuanku Bainun Fakulti Sains dan Matematik N/A
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| spellingShingle |
Norzafneza Mohd Arriffin
Chemical constituents of Malaysian Aquilaria crassna Pierre (gaharu)
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| thesis_level |
Master
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| title |
Chemical constituents of Malaysian Aquilaria crassna Pierre (gaharu)
|
| title_full |
Chemical constituents of Malaysian Aquilaria crassna Pierre (gaharu)
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| title_fullStr |
Chemical constituents of Malaysian Aquilaria crassna Pierre (gaharu)
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| title_full_unstemmed |
Chemical constituents of Malaysian Aquilaria crassna Pierre (gaharu)
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| title_short |
Chemical constituents of Malaysian Aquilaria crassna Pierre (gaharu)
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| title_sort |
chemical constituents of malaysian aquilaria crassna pierre gaharu
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| url |
https://ir.upsi.edu.my/detailsg.php?det=13225
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| work_keys_str_mv |
AT norzafnezamohdarriffin chemicalconstituentsofmalaysianaquilariacrassnapierregaharu
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