Extraction and isolation of alkaloids from the leaves of alseodaphne corneri (Lauraceae)

Bibliographic Details
Main Author: Jennie, Khoo Hui Chen
Format: Thesis
Language:English
Published: 2015
Subjects:
Online Access:https://ir.upsi.edu.my/detailsg.php?det=1639
Abstract Abstract here
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author Jennie, Khoo Hui Chen
author_facet Jennie, Khoo Hui Chen
author_sort Jennie, Khoo Hui Chen
description
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institution Universiti Pendidikan Sultan Idris
language English
publishDate 2015
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spelling upsi-16392020-02-27 Extraction and isolation of alkaloids from the leaves of alseodaphne corneri (Lauraceae) 2015 Jennie, Khoo Hui Chen QD Chemistry This phytochemical study is aimed to extract, isolate and identify alkaloids from Alseodaphne corneri leaves. The crude alkaloid was extracted by cold percolation followed by acid-base extraction until Mayer test showed negative result. Then, it was separated by conventional chromatographic methods using column chromatography and preparative thin layer chromatography. The structural elucidation of isolated alkaloids was then carried out by spectroscopic techniques; UV, IR, NMR and HRESIMS. The structures of the compounds were also determined by comparison with previous study. Isolation of alkaloids yielded one new benzylisoquinoline; (6,7- dimethoxyisoquinolinyl)-(2',5'-dihydroxy-4'-methoxyphenyl)-methanone 68, one bisbenylisoquinoline; obamegine 49, one oxoaporphines; atheroline 71, and five aporphine; isocorydine 48, N-methyllaurotetanine 51, laurotetanine 53, lirioferine 69 and norlirioferine 70. The benzylisoquinoline type alkaloid, lirioferine 69 and atheroline 71 were first reported in Alseodaphne genus while norlirioferine 70 was first isolated from Alseodaphne corneri species. These findings are very important as the elucidated alkaloids can be referred in future especially in identification of new alkaloid compound. 2015 thesis https://ir.upsi.edu.my/detailsg.php?det=1639 https://ir.upsi.edu.my/detailsg.php?det=1639 text eng N/A openAccess Masters Universiti Pendidikan Sultan Idris Fakulti Sains dan Matematik N/A
spellingShingle QD Chemistry
Jennie, Khoo Hui Chen
Extraction and isolation of alkaloids from the leaves of alseodaphne corneri (Lauraceae)
thesis_level Master
title Extraction and isolation of alkaloids from the leaves of alseodaphne corneri (Lauraceae)
title_full Extraction and isolation of alkaloids from the leaves of alseodaphne corneri (Lauraceae)
title_fullStr Extraction and isolation of alkaloids from the leaves of alseodaphne corneri (Lauraceae)
title_full_unstemmed Extraction and isolation of alkaloids from the leaves of alseodaphne corneri (Lauraceae)
title_short Extraction and isolation of alkaloids from the leaves of alseodaphne corneri (Lauraceae)
title_sort extraction and isolation of alkaloids from the leaves of alseodaphne corneri lauraceae
topic QD Chemistry
url https://ir.upsi.edu.my/detailsg.php?det=1639
work_keys_str_mv AT jenniekhoohuichen extractionandisolationofalkaloidsfromtheleavesofalseodaphnecornerilauraceae