Molecular Cloning, Expression, And Characterization Of Glutathione-Stransferase As A Novel Target In Antimalarial Drug Design And Discovery

Glutation-S-transferase (GSTs) adalah sekumpulan enzim detoksifikasi. Plasmodium falciparum mempunyai isoform tunggal GST (PfGST) yang terlibat dalam bagi detoksifikasi heme. The Glutathione-S-transferases (GSTs) are group of detoxification enzymes. Plasmodium falciparum has a single isoform o...

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मुख्य लेखक: Al-Qattan, Mohammed Nooraldeen Mahmod
स्वरूप: थीसिस
भाषा:अंग्रेज़ी
प्रकाशित: 2015
विषय:
QH1 Natural history (General - Including nature conservation, geographical distribution)
ऑनलाइन पहुंच:http://eprints.usm.my/30219/
Abstract Abstract here
विवरण
सारांश:Glutation-S-transferase (GSTs) adalah sekumpulan enzim detoksifikasi. Plasmodium falciparum mempunyai isoform tunggal GST (PfGST) yang terlibat dalam bagi detoksifikasi heme. The Glutathione-S-transferases (GSTs) are group of detoxification enzymes. Plasmodium falciparum has a single isoform of GST (PfGST) that involves in heme detoxification. While other GSTs isoforms from human (hGSTP1) and mouse (mGSTM1) are involved in apoptotic stress kinase pathway and mediate cancer cell resistance to chemotherapy.

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