Synthesis And Biological Activity Of Benzimidazole Analogs As Sirtuin Enzyme Inhibitors
Bagi mencari perencat enzim sirtuin yang poten, 90 analog benzimidazol telah berjaya direka.Kaedah sintesis yang digunakan dalam projek ini mengambilkira langkah-langkah yang lestari.Sebatian4h (ethyl 2-(4-(piperidin-1-yl)phenyl)-1H-benzo[d]imidazole-5-carboxylate)merupakanperencat enzim sirtuin yan...
| Auteur principal: | Yeong, Keng Yoon |
|---|---|
| Format: | Thèse |
| Langue: | anglais |
| Publié: |
2016
|
| Sujets: | |
| Accès en ligne: | http://eprints.usm.my/32341/ |
| Abstract | Abstract here |
Documents similaires
A Novel Inhibitor Of Sirtuin: Elucidation Of Mode Of Action And Molecular Pathway In Colorectal Cancer Cell Line
par: Tan, Yi Jer
Publié: (2017)
par: Tan, Yi Jer
Publié: (2017)
Screening And Characterisation Of Inhibitors For Glyoxylate Cycle ICL Enzyme Activity In Candida Albicans
par: Cheah, Hong Leong
Publié: (2014)
par: Cheah, Hong Leong
Publié: (2014)
Synthesis, Biological Activity And Molecular Docking Of Imidazole-Phenazine Derivatives As Potential Inhibitors For Ns2b-Ns3 Dengue Protease
par: Khalili, Nur Sarah Dyana
Publié: (2024)
par: Khalili, Nur Sarah Dyana
Publié: (2024)
Computational Design And Synthesis Of Potential Ns2b-Ns3 Dengue Protease Inhibitors
par: Salin, Nurul Hanim
Publié: (2024)
par: Salin, Nurul Hanim
Publié: (2024)
Isolation And Selective Reduction Of Mitragynine, Synthesis And Characterization Of New Indole Derivatives And Their Selected Biological Activity Studies
par: Goh, Teik Beng
Publié: (2015)
par: Goh, Teik Beng
Publié: (2015)
Characterization of the anti-angiogenesis activity of labisia pumila and identification of its molecular constituents that contribute to its biological activity.
par: Samad, Nozlena Abdul
Publié: (2010)
par: Samad, Nozlena Abdul
Publié: (2010)
Daily Rhythms In Insecticide Susceptibility, Metabolic Enzyme Activity And Gene Expression In The Common Bed Bug, Cimex lectularius L. (Hemiptera: Cimicidae)
par: Khalid, Muhammad Fazli
Publié: (2020)
par: Khalid, Muhammad Fazli
Publié: (2020)
Screening For Potential Inhibitors Of Mycobacterium Tuberculosis Isocitrate Lyase: In Silico And In Vitro Approaches
par: Lee , Yie Vern
Publié: (2017)
par: Lee , Yie Vern
Publié: (2017)
High Throughput Virtual Screening For Inhibitors Of Salmonella typhi’s Dalanine- D-Alanine Ligase A
par: Tan, Chen Shen
Publié: (2015)
par: Tan, Chen Shen
Publié: (2015)
Effect Of Galactose And Fructose On The Expression Of Isocitrate Lyase (ICL1) Enzyme In Candida Albicans
par: Ting, Seng Yeat
Publié: (2016)
par: Ting, Seng Yeat
Publié: (2016)
Genetic Polymorphisms In The Phase I And Phase II Xenobiotic Metabolizing Enzymes In Malaysian Population And Their Influence On Colorectal Cancer Susceptibility
par: Shahpudin, Siti Nurfatimah Mohd
Publié: (2012)
par: Shahpudin, Siti Nurfatimah Mohd
Publié: (2012)
Synthesis And Characterisation Of Silver Nanoparticles Using Vernonia cinerea Aqueous Extract And Their Cytotoxic Activity Against Kasumi-1 Cell Line
par: Mohamad Zani, Radhiyatul Akma
Publié: (2016)
par: Mohamad Zani, Radhiyatul Akma
Publié: (2016)
The Effects Of Angiotensin Iconverting Enzyme (ACE) I/D And Alphaactinin- 3 (ACTN3) R/X Gene Polymorphisms On Human Physical Performance And Health Within Malaysian Population
par: Yusof @ Hanafi, Hazwani Ahmad
Publié: (2016)
par: Yusof @ Hanafi, Hazwani Ahmad
Publié: (2016)
In Vitro Evaluation Of Antifungal, Antioxidant And Cytotoxicity Activity Of Couroupita Guianensis With Identification Of Antifungal Active Fraction
par: Sivapragasam, Gothai
Publié: (2015)
par: Sivapragasam, Gothai
Publié: (2015)
Synthesis And Characterisation Of PEG-PLGA Nanoparticles For Geraniin Isolated From Phyllanthus watsonii (Dukung Anak) Extract
par: Jairaman, Sreegayathri
Publié: (2018)
par: Jairaman, Sreegayathri
Publié: (2018)
In Vitro Cytotoxicity Activity And In Vivo Oral
Toxicity Of Euphorbia hirta
par: Kwan, Yuet Ping
Publié: (2014)
par: Kwan, Yuet Ping
Publié: (2014)
Evaluation Of Antimicrobial Activity Of Eclipta Alba Leaf Extract For Food Preservation
par: Rajandran, R. Kushha
Publié: (2020)
par: Rajandran, R. Kushha
Publié: (2020)
Synthesis And Characterization Of Phenyl Functionalized Magnetic Nanoparticles As Sorbent In Micro-Solid Phase Extraction Of Polycyclic Aromatic Hyrocarbons And Organophosphorus Pesticides
par: Hassan, Farah Wahidah Mohd
Publié: (2018)
par: Hassan, Farah Wahidah Mohd
Publié: (2018)
Antimicrobial, Anticancer And Antioxidant Activities Of Methanolic Extract Of Elaeis Guineensis Jacq. Leaves
par: Soundararajan, Vijayarathna
Publié: (2012)
par: Soundararajan, Vijayarathna
Publié: (2012)
Caloric Content Has Greater Level Of Brain Activation During Carbohydrate Mouth Rinsing
par: Abu Bakar, Al-Hafiz
Publié: (2017)
par: Abu Bakar, Al-Hafiz
Publié: (2017)
Screening Of Agro-Wastes As Growth
Substrate, Quantification And
Antimicrobial Activity Of Bioactive
Metabolites Of Lactobacillus Species
par: Ali Hassan, Hassan Pyar
Publié: (2015)
par: Ali Hassan, Hassan Pyar
Publié: (2015)
Anti-Candidal Activity And Toxicity Studies Of Alginate-Enclosed Chitosan–Calcium Phosphate-Loaded Fe-Bovine Lactoferrin Nanocapsules
par: Khoo, Miew Leng
Publié: (2018)
par: Khoo, Miew Leng
Publié: (2018)
Effects Of Chrysin On The mRNA Expression Of Peroxisome Proliferator-Activated Receptor Alpha (PPARα) And Cyp Genes, Cell Cycle And Cell Migration In Colorectal Cancer Hct-116 Cells
par: Khor, Chin Yin
Publié: (2020)
par: Khor, Chin Yin
Publié: (2020)
A comparative study on the effectiveness of adjunct online learning tool between conventional and gamified e-learning in enhancing electrocardiogram competency among medical students
par: May Honey Ohn
Publié: (2019)
par: May Honey Ohn
Publié: (2019)
Identification Of Salmonella Enterica Subspecies Enterica Serovar Typhi-Specific Genes For The Development Of
Dna-Based And Antibody-Based Diagnostics For Typhoid Fever
par: Goay , Yuan Xin
Publié: (2018)
par: Goay , Yuan Xin
Publié: (2018)
Detection And Identification Of Circulating Toxoplasma Gondii Antigens And Host Specific Proteins In Toxoplasmosis Via Serum Proteomic Approach
par: Osman, Emelia
Publié: (2010)
par: Osman, Emelia
Publié: (2010)
Construction Of Human Lymphatic Filariasis Antibody Phage Display Library And Production Of Recombinant Monoclonal Antibodies Against BmR1 And BmSXP Filarial Antigens
par: Rahumatullah, Anizah
Publié: (2018)
par: Rahumatullah, Anizah
Publié: (2018)
Functional Characterization Of The Outer Membrane Protein TolC of Salmonella enterica subspecies enterica serovar Typhi And Its Association With Virulence
par: Hussain, Ashraf
Publié: (2018)
par: Hussain, Ashraf
Publié: (2018)
Innovative Approaches Towards Development And Utilization Of Dna Diagnostics For Salmonella Typhi.
par: Ismail, Aziah
Publié: (2009)
par: Ismail, Aziah
Publié: (2009)
Experimental Rnomics: Towards The
Identification And Characterization Of
Non-Protein-Coding Ribonucleic Acids In
Pathogenic Agent, Salmonella Typhi
par: Zakaria, Robaiza
Publié: (2008)
par: Zakaria, Robaiza
Publié: (2008)
Study On The Involvement Of Wif-1 In
Oral Carcinogenesis Via Egfr And Wnt
Signaling Pathways
par: Chow , Tan Wei
Publié: (2015)
par: Chow , Tan Wei
Publié: (2015)
Identification And Characterization Of Protein
Markers And Development Of Immunoassay For
The Detection Of Hydatid Cyst Disease
par: Moghadam Kakhki, Zohreh Kazemi
Publié: (2015)
par: Moghadam Kakhki, Zohreh Kazemi
Publié: (2015)
In-Vivo Induced Antigens
Of Toxoplasma Gondii And Their Application
In Diagnosis Of Human Toxoplasmosis
par: Amerizadeh, Atefeh
Publié: (2015)
par: Amerizadeh, Atefeh
Publié: (2015)
Studies Of Clitoria Ternatea Linn. Root
Extract On Behavioural Effects And In
Vivo Hippocampal Synaptic Plasticity In
A Rat Model Of Chronic Cerebral
Hypoperfusion
par: Damodaran, Thenmoly K
Publié: (2018)
par: Damodaran, Thenmoly K
Publié: (2018)
Development Of HSPX Vaccine Against Latent Tuberculosis Using Adjuvant-Dependent T-Helper Alternating Peptide Strategy
par: Lew, Min Han
Publié: (2020)
par: Lew, Min Han
Publié: (2020)
Cell-Based Therapy Of Human Adipose- Derived Mesenchymal Stem Cell Expressing Angiopoietin-1 In An Experimental Model Of Airway Inflammation
par: Halim, Nur Shuhaidatul Sarmiza Abdul
Publié: (2018)
par: Halim, Nur Shuhaidatul Sarmiza Abdul
Publié: (2018)
Analysis of Toxoplasma gondii excretory secretory antigens (ESA) And identification of Potential markers of acute infection.
par: Saadatnia, Geita
Publié: (2011)
par: Saadatnia, Geita
Publié: (2011)
Effects of cross-fostering and Melatonin supplementation on the Development of hypertension and Renal antioxidant/oxidant system in Spontaneously hypertensive rats.
par: Lee, Siew Keah
Publié: (2011)
par: Lee, Siew Keah
Publié: (2011)
Development Of Fӧrster Resonance Energy Transfer Based Homogeneous Immunoassays For Determination Of (R)-Methadone
par: Ooi, May Yui
Publié: (2016)
par: Ooi, May Yui
Publié: (2016)
Identification Of Potential Toxoplasma Gondii cDNA Phage Clones And Production Of The Corresponding Recombinant Proteins In The Development Of IgG Avidity Assay For Serodiagnosis Of Toxoplasmosis
par: Teh, Ai Ying
Publié: (2016)
par: Teh, Ai Ying
Publié: (2016)
Documents similaires
-
A Novel Inhibitor Of Sirtuin: Elucidation Of Mode Of Action And Molecular Pathway In Colorectal Cancer Cell Line
par: Tan, Yi Jer
Publié: (2017) -
Screening And Characterisation Of Inhibitors For Glyoxylate Cycle ICL Enzyme Activity In Candida Albicans
par: Cheah, Hong Leong
Publié: (2014) -
Synthesis, Biological Activity And Molecular Docking Of Imidazole-Phenazine Derivatives As Potential Inhibitors For Ns2b-Ns3 Dengue Protease
par: Khalili, Nur Sarah Dyana
Publié: (2024) -
Computational Design And Synthesis Of Potential Ns2b-Ns3 Dengue Protease Inhibitors
par: Salin, Nurul Hanim
Publié: (2024) -
Isolation And Selective Reduction Of Mitragynine, Synthesis And Characterization Of New Indole Derivatives And Their Selected Biological Activity Studies
par: Goh, Teik Beng
Publié: (2015)
