The Incremental Value Of I-131 Spect/ct Of The Neck In The Management Of Differentiated Thyroid Carcinoma

• Main Author: Mohamad Najib, Fatin Hayyani
• Format: Thesis
• Language: English
• Published: 2017
• Subjects: RK1-715 Dentistry
• Online Access: http://eprints.usm.my/40599/

Tujuan: Untuk mengkaji penambahan nilai klinikal oleh SPECT/CT leher dan pengaruh ke atas rawatan pesakit “differentiated thyroid carcinoma”. Metodologi: Skan radioiodin I-131 seluruh badan secara planar dan SPECT/CT leher dijalankan ke atas 78 pesakit yang telah disahkan secara histopatologi mengidap “differentiated thyroid carcinoma”. Hasil skan seluruh badan secara planar dan SPECT/CT leher telah dianalisis. Analisa klinikal berdasarkan klasifikasi TNM untuk tahap kanser, status kumpulan stratifikasi risiko terjadinya kanser berulang dan rancangan rawatan dibuat berdasarkan hasil skan seluruh badan secara planar dan SPECT/CT leher dan dibuat perbandingan. Seterusnya, analisa ini digunakan untuk menilai kesan atau impak terhadap perancangan rawatan pesakit secara keseluruhan. The incremental value of I-131 SPECT/CT of the neck in the management of differentiated thyroid carcinoma. Aim: To assess the clinical value of single-photon emission computed tomography/computed tomography (SPECT/CT) of the neck in the management of differentiated thyroid carcinoma (DTC). Material and methods: I-131 planar whole body scan and SPECT/CT of the neck were performed in 78 patients with histologically confirmed diagnosis of differentiated thyroid carcinoma. The scan findings made by each I-131 planar whole body scan and SPECT/CT of the neck were analysed. Clinical staging based on TNM staging classification and risk stratification group were assessed and compared based on information given by each I-131 planar whole body scan and SPECT/CT of the neck. Subsequently, clinical management plan made by each planar and SPECT/CT of the neck were assessed and compared for significant impact on overall patient management.