Determination Of Mitragynine As A Substrate, Inducer, Or Inhibitor Of P-Glycoprotein Drug Transporter, And Prediction Of Drug-Herb Interaction Risks

P-glycoprotein (P-gp) is a multidrug transporter, mainly expressed in the intestinal tissue as a secretory efflux protein. Changes in the activity, gene and protein expression of P-gp caused by drugs or herbal compounds will affect oral drug bioavailability and may potentially lead to drug-drug or d...

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