The effect of budesonide and 5-azacytidine on the levels of methylation at the CpG islands of human choline kinase alpha (ckα) and beta (ckβ) promoter
Choline kinase (CK) is the first enzyme in the CDP-choline pathway for the synthesis of phosphotidylcholine, a major component of membrane phospholipid. In human, CK is encoded by ckα and ckβ genes which produce three protein isoforms known as CKα1, CKα2 and CKβ. CKα is involved in tumorigenesis whi...
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| Format: | Thèse |
| Langue: | anglais |
| Publié: |
2017
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| Accès en ligne: | http://eprints.usm.my/43111/ |
| Abstract | Abstract here |