Influence of ORM1, PXR, CAR, CYP3A4 and CYP3A5 gene polymorphisms in mediating susceptibility risk to chronic myeloid leukaemia and response to imatinib mesylate therapy

Genetic polymorphisms are well recognized sources of individual differences in disease risk and treatment response. Associations between human genetic variants and predisposition to diseases and adverse events for different kinds of drug interactions with hundreds of protein like receptors, trans...

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Détails bibliographiques
Auteur principal:	Maddin, Najlaa
Format:	Thèse
Langue:	anglais
Publié:	2017
Sujets:	R Medicine (General)
Accès en ligne:	http://eprints.usm.my/43138/

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