Design, Synthesis, Cytotoxic Activity And DNA Intercalation Of New β-Carboline Derivatives

The focus of this study has been to investigate the in vitro cytotoxic effects of new β-carboline derivatives on the K562 human cancer cell line. Analysis using 3D-QSAR models has revealed the importance of derivatisation at position-2 and -9 of the β-carbolines. Two new series of N2-benzylated-β-ca...

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Auteur principal: Mohideen, Mazlin
Format: Thèse
Langue:anglais
Publié: 2018
Sujets:
Accès en ligne:http://eprints.usm.my/43676/
Abstract Abstract here