Isolation And Characterization Of Marine Actinomycetes For Anti-Infective Activity Towards Pseudomonas aeruginosa PA14

Marine environment serve as reservoir of vast useful secondary metabolites and at the same time, new anti-infective agents are required to combat antibiotic resistant pathogenic bacteria.Therefore, this research was carried out to screen for anti-infective agents from the environment that are capabl...

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Main Author: Kamal, Siti Nur Fatin Ahmad
Format: Thesis
Language:English
Published: 2018
Subjects:
Online Access:http://eprints.usm.my/43755/
Abstract Abstract here
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author Kamal, Siti Nur Fatin Ahmad
author_facet Kamal, Siti Nur Fatin Ahmad
author_sort Kamal, Siti Nur Fatin Ahmad
description Marine environment serve as reservoir of vast useful secondary metabolites and at the same time, new anti-infective agents are required to combat antibiotic resistant pathogenic bacteria.Therefore, this research was carried out to screen for anti-infective agents from the environment that are capable of overcoming Pseudomonas aeruginosa infection through anti-virulence or boosting of host immunity activities. Marine soil sediments were collected from Songsong Island, Yan, Kedah, Malaysia and a total of 18 actinomycetes with different morphology were successfully isolated. Secondary metabolites from all isolates were extracted out using solid-liquid extraction method and were screened for anti-infective activity using Caenorhabditis elegans infection model.
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spelling usm-437552019-04-12T05:24:51Z http://eprints.usm.my/43755/ Isolation And Characterization Of Marine Actinomycetes For Anti-Infective Activity Towards Pseudomonas aeruginosa PA14 Kamal, Siti Nur Fatin Ahmad QH1 Natural history (General - Including nature conservation, geographical distribution) Marine environment serve as reservoir of vast useful secondary metabolites and at the same time, new anti-infective agents are required to combat antibiotic resistant pathogenic bacteria.Therefore, this research was carried out to screen for anti-infective agents from the environment that are capable of overcoming Pseudomonas aeruginosa infection through anti-virulence or boosting of host immunity activities. Marine soil sediments were collected from Songsong Island, Yan, Kedah, Malaysia and a total of 18 actinomycetes with different morphology were successfully isolated. Secondary metabolites from all isolates were extracted out using solid-liquid extraction method and were screened for anti-infective activity using Caenorhabditis elegans infection model. 2018-05 Thesis NonPeerReviewed application/pdf en http://eprints.usm.my/43755/1/SITI%20NUR%20FATIN%20AHMAD%20KAMAL.pdf Kamal, Siti Nur Fatin Ahmad (2018) Isolation And Characterization Of Marine Actinomycetes For Anti-Infective Activity Towards Pseudomonas aeruginosa PA14. Masters thesis, Universiti Sains Malaysia.
spellingShingle QH1 Natural history (General - Including nature conservation, geographical distribution)
Kamal, Siti Nur Fatin Ahmad
Isolation And Characterization Of Marine Actinomycetes For Anti-Infective Activity Towards Pseudomonas aeruginosa PA14
thesis_level Master
title Isolation And Characterization Of Marine Actinomycetes For Anti-Infective Activity Towards Pseudomonas aeruginosa PA14
title_full Isolation And Characterization Of Marine Actinomycetes For Anti-Infective Activity Towards Pseudomonas aeruginosa PA14
title_fullStr Isolation And Characterization Of Marine Actinomycetes For Anti-Infective Activity Towards Pseudomonas aeruginosa PA14
title_full_unstemmed Isolation And Characterization Of Marine Actinomycetes For Anti-Infective Activity Towards Pseudomonas aeruginosa PA14
title_short Isolation And Characterization Of Marine Actinomycetes For Anti-Infective Activity Towards Pseudomonas aeruginosa PA14
title_sort isolation and characterization of marine actinomycetes for anti infective activity towards pseudomonas aeruginosa pa14
topic QH1 Natural history (General - Including nature conservation, geographical distribution)
url http://eprints.usm.my/43755/
work_keys_str_mv AT kamalsitinurfatinahmad isolationandcharacterizationofmarineactinomycetesforantiinfectiveactivitytowardspseudomonasaeruginosapa14