The Effect Of Mitragynine On Cyclic Amp Formation And Mrna Expression Of Mu-Opioid Receptors Mediated By Chronic Morphine Treatment In Sk-N-Sh Neuroblastoma Cell

Mitragynine is an indole alkaloid compound of Mitragyna speciosa (M.speciosa) Korth. (Rubiaceae). In Thailand, this plant is known as “Kratom” and in Malaysia it is known as “Biak-biak” or “Ketum”. M. speciosa was used as substitution therapy for chronic opioid treatment to manage the withdraw...

Full description

Bibliographic Details
Main Author:	Jamil, Mohd Fadzly Amar
Format:	Thesis
Language:	English
Published:	2013
Subjects:	RS1-441 Pharmacy and materia medica
Online Access:	http://eprints.usm.my/43825/
Abstract	Abstract here

Similar Items

2020_The Effect of Nigella Sativa Linn on cAMP & MU-OPIOID Receptor Protein Levels in Morphine-Treated U-87 MG Cell Line
by: Nor Zidah Binti Ahmad
Published: (2020)

2018_Effects of Zamzam Water on Mu-Opioid Receptor Gene Expression in Morphine Dependent Subjects
by: Mohamad Halim Bin Mohamad Shariff
Published: (2018)

Effects of haruan pressurized in water extract on SK-N-SH human neuroblastoma cell line in vitro
by: Ibrahim, Buhari
Published: (2015)

Comparison of the effect of chronic treatment of mitragynine and morphine on antinociceptive behaviour and cAMP-PKA RIIβ genes expression in mice
by: Akhir, Sakinah Mohd
Published: (2018)

Neuroprotective effect of Caulerpa lentillifera extracts against lipopolysaccharide-induced neuroinflammation in raw 264.7 macrophages and SK-N-SH neuroblastoma cells
by: Hamli, Aiman
Published: (2025)

A Pilot Study On The A118g Mu Opioid Receptor Polymorphism Among Drug Addicts In Malaysia
by: Nagaya, Devaki
Published: (2010)

Effects of Erythroxylum Cuneatum (Miq.) Kurz on cellular and synaptic adaptation of chronic morphine-addicted human neuroblastoma cell line at protein level
by: Sulaiman, Noor Azuin
Published: (2017)

Behavioural, Biochemical, Proteomics Studies And Replacement Therapy Of Morphine And Mitragynine Withdrawal Rat Models
by: Hassan, Rahimah
Published: (2021)

Kesan apoptotik dan antioksidatif gama-tokotrienol terhadap sel neuroblastoma manusia sh-sy5y
by: Tan Jen Kit (P59459)
Published: (2023)

Assessment of dopamine receptor drd4 and drd5 mrna expression in peripheral blood lymphocytes of opioid & amphetamine type stimulant dependent Malay men undergoing methadone maintenance therapy
by: Jamil, Nur Khadijah Muhamad
Published: (2020)

Cross-reinstatement Models Of Mitragynine-morphine Drugseeking Addictive Behaviour And Dopaminergic Involvement In Sprague-dawley Rats
by: Japarin, Rima Atria
Published: (2024)

2019_Effect of Phenolic Acids in Pomegranate (Punica Granatum) Extract as Non-Opioid Substitution Therapy for Morphine Dependent Treatment
by: Mimie Noratiqah Jumli
Published: (2019)

Neuroprotective effect of selected herbs on H2O2-induced neuroblastoma cell damage in SH-SY5Y / Farah Azirah Mohd Yusuf
by: Farah Azirah , Mohd Yusuf
Published: (2019)

Neuroprotective effect of Centella asiatica (L.) Urb. against toxicity induced by different neurotoxic agents in neuroblastoma SH-SY5Y cells / Heymmela Kasi
by: Heymmela , Kasi
Published: (2019)

The Effects Of Mitragynine From Mitragyna Speciosa On The Mrna Expression Of Cox-1 And Cox-2 In Lipopolysaccharide-Stimulated Raw264.7 Macrophage Cells
by: Utar, Zulkhurnain
Published: (2014)

The Effects Of Mitragynine From Mitragyna Speciosa On The Mrna Expression Of Cox-1 And Cox-2 In Lipopolysaccharide-Stimulated Raw264.7 Macrophage Cells
by: Utar, Zulkhurnain
Published: (2014)

Polyvinyl alcohol-grafted-multiwalled carbon nanotubes as a delivery system for curcumin in H2O2-induced damaged neuroblastoma SH-SY5Y cells
by: Nurliyana Ahmad Zawawi
Published: (2025)

The effect of gamma irradiation on selected growth factors and receptors mRNA in glycerol cryopreserved human amniotic membrane
by: Mat Yatim, Rusidah
Published: (2015)

Neuroprotective effect of virgin coconut oil on lipopoly saccharide-induced cell death in SK-N-SH and memory impairment in rat / Nur Syafiqah Rahim
by: Rahim, Nur Syafiqah
Published: (2015)

The effects of chronic administration of mitragynine on cortical oscillations in rats
by: Doraisamy, Thilageswary a/p
Published: (2022)

Investigating the involvement of kappa opioid receptor in mediating relapse related to morphne/methamphetamine (poly-drug) dependence using an immunohistochemistry technique
by: Nur Syafinaz binti Wasli
Published: (2024)

Development Of An Immunoassay For Mitragynine
by: Lee , Mei Jin
Published: (2016)

A study of the &quot;Aphasia&quot; in Eileen Chang&#039;s novels
by: Ji, Zhongxuan
Published: (2025)

2018_The Effects of Thymoquinone as Potential Novel Supplements Therapy for Better Outcome on Methadone Maintenance Therapy in Opioid Receptor Expressing Cell Line (Orec)
by: Liyana Hazwani Binti Mohd Adnan
Published: (2018)

Randomised double-blind comparison of morphine vs a morphine-alfentanil combination for patient-controlled analgesia
by: Alias, Anita
Published: (2002)

Islamisasi ilmu dan implikasinya kepada falsafah dan sistem pendidikan negara / SH. Azad SH. Attar.
by: SH. Attar, SH. Azad
Published: (2001)

Identification and characterization of fungal strain SH1,SH_1 and RD2_1 isolated from mangrove soil
by: Mohd. Shukri Hassan
Published: (2025)

Synthesis, Characterization And Analgesic Activity Of Mitragynine Analogues
by: Ramlee, Nurul Izzati
Published: (2015)

Pharmacokinetic And Pharmacodynamic Modeling Of Mitragynine In PainTolerance
by: Ramachandram, Dinesh Sangarran
Published: (2020)

Investigation Of In Vitro Permeation Of Mitragynine Through The Skin
by: Sim, Yee Shan
Published: (2023)

Penggunaan elemen &amp; teknik web e-pembelajaran muzik : satu kajian perbandingan
by: Suhairi Shoib
Published: (2000)

Mitologi dalam \&quot;Menanti Puteri Hijau\&quot; karya Ismail Kassan
by: Nasir Razali
Published: (2017)

Effects Of Chrysin On The mRNA Expression Of Peroxisome Proliferator-Activated Receptor Alpha (PPARα) And Cyp Genes, Cell Cycle And Cell Migration In Colorectal Cancer Hct-116 Cells
by: Khor, Chin Yin
Published: (2020)

The role of mesolimbic system and lateral habenular molecular targets (CB₁, GluA₁ and NK₁ receptors) in mitragyna speciosa korth (ketum) addiction in the mitragynine-sensitised swiss albino mice
by: Ismail, Nurul Iman Wan
Published: (2021)

Kata sendi nama &#039;Pada&#039; dan &#039;Kepada&#039; dalam Bahasa Melayu: perbandingan antara teks Tatabahasa Dewan dengan data korpus Dewan Bahasa dan Pustaka
by: Mohd Pouzi Zakaria
Published: (2008)

Efficacy and safety on non-opioid based versus opioid-based multimodal analygesia in patients undergoing elective laporoscopic cholecystectomy : a randomized controlled trial
by: Khairuddin, Khuzaimah
Published: (2020)

Postpartum depression determination through machine learning algorithms Open acess theses &amp; dissertation
by: Winda Ayu Fazraningtyas
Published: (2025)

Pharmacokinetics And Investigation Of The Anxiolytic-Like Effect Of Mitragynine In Rats
by: Imad Hazim Al Ganaby, Ammar
Published: (2016)

Evaluation Of Rat In Situ Intestinal Permeability Study Of Mitragynine
by: Jagabalan, J.D.Yuvenesan
Published: (2016)

The Effect Of Mitragynine Addiction In Rats On Histone Regulations And Neuroplasticity
by: Suleiman, Yunusa
Published: (2024)