Isolation And Characterisation Of Chemical Constituents With Anti-Methicilin Resistant Staphylococcus Aureus Activity From Mesua Ferrea Leaf Extract

The present study aims to isolate compounds with antimicrobial activity from Mesua ferrea leaf employing bioassay guided approach. An antibacterial assay guided extraction and compound isolation procedure was carried out on Mesua ferrea methanolic leaf extract with a number of Gram positives and neg...

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Main Author: Alagasamy, Sangeeta Vani
Format: Thesis
Language:English
Published: 2018
Subjects:
Online Access:http://eprints.usm.my/44340/
Abstract Abstract here
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author Alagasamy, Sangeeta Vani
author_facet Alagasamy, Sangeeta Vani
author_sort Alagasamy, Sangeeta Vani
description The present study aims to isolate compounds with antimicrobial activity from Mesua ferrea leaf employing bioassay guided approach. An antibacterial assay guided extraction and compound isolation procedure was carried out on Mesua ferrea methanolic leaf extract with a number of Gram positives and negatives bacteria. Firstly, M. ferrea leaf extraction technique was optimized using antimicrobial assay guided method. Powdered freeze dried leaves of M. ferrea (particle size 0.5mm) (1:15w/v) using ultrasonic-assisted technique yielded methanol crude extract with a good antibacterial activity against Staphylococcus aureus, MRSA, Pseudomonas aeruginosa, Bacillus subtilis and Escherichia coli.
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spelling usm-443402019-05-15T02:18:15Z http://eprints.usm.my/44340/ Isolation And Characterisation Of Chemical Constituents With Anti-Methicilin Resistant Staphylococcus Aureus Activity From Mesua Ferrea Leaf Extract Alagasamy, Sangeeta Vani RS200-201 Pharmaceutical dosage forms The present study aims to isolate compounds with antimicrobial activity from Mesua ferrea leaf employing bioassay guided approach. An antibacterial assay guided extraction and compound isolation procedure was carried out on Mesua ferrea methanolic leaf extract with a number of Gram positives and negatives bacteria. Firstly, M. ferrea leaf extraction technique was optimized using antimicrobial assay guided method. Powdered freeze dried leaves of M. ferrea (particle size 0.5mm) (1:15w/v) using ultrasonic-assisted technique yielded methanol crude extract with a good antibacterial activity against Staphylococcus aureus, MRSA, Pseudomonas aeruginosa, Bacillus subtilis and Escherichia coli. 2018-05 Thesis NonPeerReviewed application/pdf en http://eprints.usm.my/44340/1/SANGEETA%20VANI%20ALAGASAMY.pdf Alagasamy, Sangeeta Vani (2018) Isolation And Characterisation Of Chemical Constituents With Anti-Methicilin Resistant Staphylococcus Aureus Activity From Mesua Ferrea Leaf Extract. Masters thesis, Universiti Sains Malaysia.
spellingShingle RS200-201 Pharmaceutical dosage forms
Alagasamy, Sangeeta Vani
Isolation And Characterisation Of Chemical Constituents With Anti-Methicilin Resistant Staphylococcus Aureus Activity From Mesua Ferrea Leaf Extract
thesis_level Master
title Isolation And Characterisation Of Chemical Constituents With Anti-Methicilin Resistant Staphylococcus Aureus Activity From Mesua Ferrea Leaf Extract
title_full Isolation And Characterisation Of Chemical Constituents With Anti-Methicilin Resistant Staphylococcus Aureus Activity From Mesua Ferrea Leaf Extract
title_fullStr Isolation And Characterisation Of Chemical Constituents With Anti-Methicilin Resistant Staphylococcus Aureus Activity From Mesua Ferrea Leaf Extract
title_full_unstemmed Isolation And Characterisation Of Chemical Constituents With Anti-Methicilin Resistant Staphylococcus Aureus Activity From Mesua Ferrea Leaf Extract
title_short Isolation And Characterisation Of Chemical Constituents With Anti-Methicilin Resistant Staphylococcus Aureus Activity From Mesua Ferrea Leaf Extract
title_sort isolation and characterisation of chemical constituents with anti methicilin resistant staphylococcus aureus activity from mesua ferrea leaf extract
topic RS200-201 Pharmaceutical dosage forms
url http://eprints.usm.my/44340/
work_keys_str_mv AT alagasamysangeetavani isolationandcharacterisationofchemicalconstituentswithantimethicilinresistantstaphylococcusaureusactivityfrommesuaferrealeafextract