The Effects Of Stichopus Variegatus Crude Extracts On Acute Contusive Rat Spinal Cord Injury Model : In Vitro And In Vivo Studies
Sea cucumbers from Pulau Perhentian, Malaysia are well known as potential marine edible food sources and possess medicinal value to the Malaysian community. Despite the presence of small industries and its usage amongst local folks, there is little work done on its biological activity, especially on...
| المؤلف الرئيسي: | |
|---|---|
| التنسيق: | أطروحة |
| اللغة: | الإنجليزية |
| منشور في: |
2012
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| الموضوعات: | |
| الوصول للمادة أونلاين: | http://eprints.usm.my/44845/ |
| Abstract | Abstract here |
| _version_ | 1855632330599694336 |
|---|---|
| author | Ab Patar, Mohd Nor Azim |
| author_facet | Ab Patar, Mohd Nor Azim |
| author_sort | Ab Patar, Mohd Nor Azim |
| description | Sea cucumbers from Pulau Perhentian, Malaysia are well known as potential marine edible food sources and possess medicinal value to the Malaysian community. Despite the presence of small industries and its usage amongst local folks, there is little work done on its biological activity, especially on the central nervous system. In the present study, Stichopus variegatus (SV) were harvested, processed and extracted in the laboratory and were evaluated on their proliferative activity on rat astrocytes cell lines (in vitro), as well as contusive spinal cord injury in a rat model (in vivo). In vitro
analysis of SV extract showed proliferative activity of rat astrocytes cell line at 5 μg/ml and 10 μg/ml. |
| first_indexed | 2025-10-17T08:25:28Z |
| format | Thesis |
| id | usm-44845 |
| institution | Universiti Sains Malaysia |
| language | English |
| last_indexed | 2025-10-17T08:25:28Z |
| publishDate | 2012 |
| record_format | EPrints |
| record_pdf | Restricted |
| spelling | usm-448452019-07-03T07:19:38Z http://eprints.usm.my/44845/ The Effects Of Stichopus Variegatus Crude Extracts On Acute Contusive Rat Spinal Cord Injury Model : In Vitro And In Vivo Studies Ab Patar, Mohd Nor Azim R5-920 Medicine (General) Sea cucumbers from Pulau Perhentian, Malaysia are well known as potential marine edible food sources and possess medicinal value to the Malaysian community. Despite the presence of small industries and its usage amongst local folks, there is little work done on its biological activity, especially on the central nervous system. In the present study, Stichopus variegatus (SV) were harvested, processed and extracted in the laboratory and were evaluated on their proliferative activity on rat astrocytes cell lines (in vitro), as well as contusive spinal cord injury in a rat model (in vivo). In vitro analysis of SV extract showed proliferative activity of rat astrocytes cell line at 5 μg/ml and 10 μg/ml. 2012-06 Thesis NonPeerReviewed application/pdf en http://eprints.usm.my/44845/1/MOHD%20NOR%20AZIM%20AB%20PATAR.pdf Ab Patar, Mohd Nor Azim (2012) The Effects Of Stichopus Variegatus Crude Extracts On Acute Contusive Rat Spinal Cord Injury Model : In Vitro And In Vivo Studies. Masters thesis, Universiti Sains Malaysia. |
| spellingShingle | R5-920 Medicine (General) Ab Patar, Mohd Nor Azim The Effects Of Stichopus Variegatus Crude Extracts On Acute Contusive Rat Spinal Cord Injury Model : In Vitro And In Vivo Studies |
| thesis_level | Master |
| title | The Effects Of Stichopus Variegatus Crude Extracts On Acute Contusive Rat Spinal Cord Injury Model : In Vitro And In Vivo Studies |
| title_full | The Effects Of Stichopus Variegatus Crude Extracts On Acute Contusive Rat Spinal Cord Injury Model : In Vitro And In Vivo Studies |
| title_fullStr | The Effects Of Stichopus Variegatus Crude Extracts On Acute Contusive Rat Spinal Cord Injury Model : In Vitro And In Vivo Studies |
| title_full_unstemmed | The Effects Of Stichopus Variegatus Crude Extracts On Acute Contusive Rat Spinal Cord Injury Model : In Vitro And In Vivo Studies |
| title_short | The Effects Of Stichopus Variegatus Crude Extracts On Acute Contusive Rat Spinal Cord Injury Model : In Vitro And In Vivo Studies |
| title_sort | effects of stichopus variegatus crude extracts on acute contusive rat spinal cord injury model in vitro and in vivo studies |
| topic | R5-920 Medicine (General) |
| url | http://eprints.usm.my/44845/ |
| work_keys_str_mv | AT abpatarmohdnorazim theeffectsofstichopusvariegatuscrudeextractsonacutecontusiveratspinalcordinjurymodelinvitroandinvivostudies AT abpatarmohdnorazim effectsofstichopusvariegatuscrudeextractsonacutecontusiveratspinalcordinjurymodelinvitroandinvivostudies |