Functional Characterization Of Styr-3 Non-Protein-Coding Rna (npcRNA) In Salmonella enterica serovar Typhi

Non-protein-coding RNAs (npcRNAs) are RNA molecules that do not encode for proteins but are involved in modulating a myriad of cell regulatory processes, including bacterial drug resistance mechanisms. In this study, a novel npcRNA, StyR-3; discovered from the genome of S. Typhi was selected for fur...

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Main Author: Kumar, Thiviyaa M. Othaya
Format: Thesis
Language:English
Published: 2014
Subjects:
R735-854 Medical education. Medical schools. Research
Online Access:http://eprints.usm.my/45075/
Abstract Abstract here
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author Kumar, Thiviyaa M. Othaya
author_facet Kumar, Thiviyaa M. Othaya
author_sort Kumar, Thiviyaa M. Othaya
description Non-protein-coding RNAs (npcRNAs) are RNA molecules that do not encode for proteins but are involved in modulating a myriad of cell regulatory processes, including bacterial drug resistance mechanisms. In this study, a novel npcRNA, StyR-3; discovered from the genome of S. Typhi was selected for further characterization via bioinformatics and experimental-based approaches. This 144-nt intergenic npcRNA is located in the ramRA regulon of S. Typhi Ty2. The bioinformatics-based characterization showed that it is highly conserved among Salmonella species; besides having a stable secondary structure as was predicted by LocaRNA software.
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spelling usm-450752019-07-26T01:25:56Z http://eprints.usm.my/45075/ Functional Characterization Of Styr-3 Non-Protein-Coding Rna (npcRNA) In Salmonella enterica serovar Typhi Kumar, Thiviyaa M. Othaya R735-854 Medical education. Medical schools. Research Non-protein-coding RNAs (npcRNAs) are RNA molecules that do not encode for proteins but are involved in modulating a myriad of cell regulatory processes, including bacterial drug resistance mechanisms. In this study, a novel npcRNA, StyR-3; discovered from the genome of S. Typhi was selected for further characterization via bioinformatics and experimental-based approaches. This 144-nt intergenic npcRNA is located in the ramRA regulon of S. Typhi Ty2. The bioinformatics-based characterization showed that it is highly conserved among Salmonella species; besides having a stable secondary structure as was predicted by LocaRNA software. 2014-12 Thesis NonPeerReviewed application/pdf en http://eprints.usm.my/45075/1/THIVIYAA%20M.%20OTHAYA%20KUMAR.pdf Kumar, Thiviyaa M. Othaya (2014) Functional Characterization Of Styr-3 Non-Protein-Coding Rna (npcRNA) In Salmonella enterica serovar Typhi. Masters thesis, Universiti Sains Malaysia.
spellingShingle R735-854 Medical education. Medical schools. Research
Kumar, Thiviyaa M. Othaya
Functional Characterization Of Styr-3 Non-Protein-Coding Rna (npcRNA) In Salmonella enterica serovar Typhi
title Functional Characterization Of Styr-3 Non-Protein-Coding Rna (npcRNA) In Salmonella enterica serovar Typhi
title_full Functional Characterization Of Styr-3 Non-Protein-Coding Rna (npcRNA) In Salmonella enterica serovar Typhi
title_fullStr Functional Characterization Of Styr-3 Non-Protein-Coding Rna (npcRNA) In Salmonella enterica serovar Typhi
title_full_unstemmed Functional Characterization Of Styr-3 Non-Protein-Coding Rna (npcRNA) In Salmonella enterica serovar Typhi
title_short Functional Characterization Of Styr-3 Non-Protein-Coding Rna (npcRNA) In Salmonella enterica serovar Typhi
title_sort functional characterization of styr 3 non protein coding rna npcrna in salmonella enterica serovar typhi
topic R735-854 Medical education. Medical schools. Research
url http://eprints.usm.my/45075/
work_keys_str_mv AT kumarthiviyaamothaya functionalcharacterizationofstyr3nonproteincodingrnanpcrnainsalmonellaentericaserovartyphi

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