Synthesis, Cholinesterase Inhibitory Activity And Molecular Docking Study Of Piperidone-Grafted Pyrimidine And Thiazolopyrimidine Derivatives
Alzheimer’s disease (AD) is the most common form of dementia among the elderly people. Based on the cholinergic hypothesis, loss of cholinergic neurons in AD patients’ brain leads to the decline of acetylcholine (ACh) neurotransmitter level and eventually causes severe dysfunctions in the cholinergi...
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| フォーマット: | 学位論文 |
| 言語: | 英語 |
| 出版事項: |
2014
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| 主題: | |
| オンライン･アクセス: | http://eprints.usm.my/46371/ |