Synthesis, Cholinesterase Inhibitory Activity And Molecular Docking Study Of Piperidone-Grafted Pyrimidine And Thiazolopyrimidine Derivatives

Alzheimer’s disease (AD) is the most common form of dementia among the elderly people. Based on the cholinergic hypothesis, loss of cholinergic neurons in AD patients’ brain leads to the decline of acetylcholine (ACh) neurotransmitter level and eventually causes severe dysfunctions in the cholinergi...

وصف كامل

التفاصيل البيبلوغرافية
المؤلف الرئيسي:	Basiri, Alireza
التنسيق:	أطروحة
اللغة:	الإنجليزية
منشور في:	2014
الموضوعات:	RS1-441 Pharmacy and materia medica
الوصول للمادة أونلاين:	http://eprints.usm.my/46371/

مواد مشابهة

Evaluation Of Various Autodock Molecular Docking Programmes In Predicting The Neuraminidase Inhibitory Activity
حسب: Raime, Nurul Nadia
منشور في: (2015)

Bioactivity-Guided Isolation Of Ailanthus Malabarica For Toxoplasma Gondii And Cholinesterase Inhibitory Activities
حسب: Lee, Yuan-E
منشور في: (2017)

In-Vitro And Molecular Docking Studies Of Seven Selected Myrtaceae Plants For Neuraminidase Activity
حسب: Ali Abdusalsalam, Ashraf Ahmed
منشور في: (2016)

Anti-Cholinesterase Activity Of Malaysian Cassia Spp. And Its Bioactive Compound
حسب: Nurul Azman, Nurul Amira
منشور في: (2020)

Synthesis, Characterization And Cholinesterase Inhibitory Activity Of Novel Piperidone Grafted Spiro Heterocycles
حسب: Kia, Yalda
منشور في: (2014)

Synthesis, Characterization And Cholinesterase Inhibitory Activity Of Novel Piperidone Grafted Spiro Heterocycles
حسب: Yalda, Kia
منشور في: (2014)

Phytochemical, Bioassay And In Silico Studies On Anti - Cholinesterase Activities Of Cassia Timoriensis Dc. And Cassia Grandis L.F.
حسب: Al-Hawarri, Maram Basem Tawfiq
منشور في: (2022)

In Vitro Antioxidant And Alpha-Glucosidase Inhibitory Activities Of Fruit Extracts From Seven Species Of Citrus
حسب: Henrietta, Ikwunne Helen
منشور في: (2018)

Development Of Electrospun Nanofibres Containing Ibuprofen Grafted Nanocrystalline Cellulose For Dermal Delivery
حسب: Ahmed Al-Mashhadani, Abdulsalam Qahtan
منشور في: (2022)

Anti-Obesity Activity Of Pandanus Amaryllifolius Roxb. And Vitex Negundo Linn. : Isolated Compounds With PTP1B Inhibitory Effects
حسب: Rathnasamy, Selestin
منشور في: (2022)

Antihyprtensive Activity Of Para-substituted Clonidine Analogues And Their Acylated Derivatives
حسب: Lewis, Alan Martin
منشور في: (1994)

Pharmacokinetics And Metabolism Studies Of Antifilarial Drugs Derivatives Of Benzimidazole Carbamate
حسب: Ramanathan, Surash
منشور في: (1996)

The Study Of Anticancer Properties Of Benzyl-O-Vanillin And Its Derivatives
حسب: Al-Mudaris, Zena A. Abdul Hameed
منشور في: (2011)

Modelling And Syntheses Of Vanillin Derivatives Targeting Influenza Virus Neuraminidase
حسب: Asaruddin, Mohd Razip
منشور في: (2016)

Molecular Dynamics Studies Of The Effects Of Neuraminidase Mutation On Oseltamivir Resistance
حسب: Muhammad Yusuf, Muhammad Yusuf
منشور في: (2015)

Studies On The Activity Of Isoniazid Derivatives And Their Combinations With Other Anti-TB Drugs On Mycobacterium Tuberculosis
حسب: Parumasivam, Thaigarajan
منشور في: (2012)

Theobromine-Based Synthetic Derivatives As Potential Inhibitors Of Dengue Virus Ii Serine Protease
حسب: Saqallah, Fadi Ghassan Mohammed
منشور في: (2023)

Molecular Modelling And Biological Evaluation Of Peptide Based Inhibitors For Dengue Virus
حسب: Ismail, Ahmad Ghazali
منشور في: (2021)

Synthesis And Application Of Molecularly Imprinted Solidphase Extraction For The Determination Of Terbutaline In Biological Matrices
حسب: Lim, Lay Lee
منشور في: (2006)

The Development Of Rosmarinic Acid Derivatives To Target Il17a In Glioblastoma Multiforme Via Angiogenic Pathways
حسب: Khan, Md Shamsuddin Sultan
منشور في: (2017)

Elucidation Of The Molecular Mechanisms Of Orthosiphon Aristatus Extract In Non-Alcoholic Fatty Liver Disease
حسب: Al Shehade, Salah Abd Alrazak
منشور في: (2023)

In Silico Prediction And In Vitro Evaluation Of Caffeic Acid And Its Derivatives As Potential Efflux Pump Inhibitor(S) In Pseudomonas Aeruginosa
حسب: Zakaria, Noor Zawani
منشور في: (2019)

Study On Traditional Medicine-modern Drug Interaction And Its Molecular Mechanism Elucidation In Rat Liver
حسب: A. Taher, Yousef
منشور في: (1998)

Synthesis Of Molecularly Imprinted Polymer For Selective Solid-Phase Extraction Of Salbutamol From Urine Samples
حسب: Lee, Wei Inn
منشور في: (2011)

Synthesis, Characterisation And Evaluation Of Biocompatible Disulphide Cross-Linked Sodium Alginate Derivative Nanoparticles For Colon Targeted Drug Delivery
حسب: Ayub, Asila Dinie
منشور في: (2018)

Structural And Functional Prediction Of Hypothetical Proteins From Klebsiella Pneumoniae MGH78578: Molecular Modelling Studies
حسب: Choi, Sy Bing
منشور في: (2011)

Molecular Dynamics Studies: The Interaction Of Erythromycin A With A Single Base Substitution Of 50s Ribosomal Subunit
حسب: Mohamad Zobir, Siti Zuraidah
منشور في: (2012)

Genotoxicity Assessment Of Standardised Root Extract Of Eurycoma Longifolia Jack And Synthesis Of Some Benzimidazole Derivatives And Evaluation Of Their Anti-Cancer Potential
حسب: Muttiah, Nithya Niranjini
منشور في: (2013)

Investigation Of Molecular Mechanisms Underlying The Anti-Tumor And Anti-Angiogenic Activities Of Orthosiphon Stamineus Towards Colorectal Cancer
حسب: Al-Suede, Fouad Saleih Resq
منشور في: (2016)

Effect Of Standardised Methanolic Extract Of Phyllanthus Niruri (Linn.) On Phase I And II Drug Metabolism And Its Molecular Mechanism Elucidation In Rat Liver
حسب: Bashir, Moath Kahtan
منشور في: (2010)

Identification Of Low Molecular Weight Metabolites That Can Predict Low Dose Aspirin Induced Gastric Toxicity And Resistance In Rats And Stable Coronary Artery Disease Patients Using Nmr-Based Pharmacometabonomics
حسب: Abubakar, Sha’aban
منشور في: (2019)

Kajian Curcumin Dari Kunyit (Curcuma Longa) Ke Atas Beberapa Parameter Fisiologi Manusia[QK495.Z65 F145 2004 f rb] [Microfiche 7545].
حسب: Tengku Kamalden, Tengku Fadilah
منشور في: (2004)

Design And Evaluation Of Prolonged Release Gliclazide Matrix Tablets.
حسب: Abdelraziq Abdelkareem Adam, Fathelrahman
منشور في: (2007)

Computational Studies Of Natural Flavonoids Towards The Discovery Of A Potential Xanthine Oxidase Inhibitor.
حسب: Mohammad Alnajjar, Belal Omar
منشور في: (2008)

Preparation And Characterization Of Water-Soluble Chitosan Gel For Skin Hydration.
حسب: Yo, Li Chen
منشور في: (2008)

Investigation of the potential of gelucire 44/14 for enhancing oral bioavailability using two model drugs [RS199.5. M211 2007 f rb].
حسب: Magosso, Enrico
منشور في: (2007)

Design And Evaluation Of Mul Tip Articulate. Systems Prepared Using Sieving-Spheronisation And Extrusionspheronisation
حسب: Karim , Sabiha
منشور في: (2011)

Establishing Halal Pharmaceuticals Information Systems: Concepts, Sources And, Potentials In The Industry
حسب: Wace, Mohammed Ali Al-Sheikh
منشور في: (2014)

Determination Of Valproic Acid Reference Range And Predictors For Good Seizure Control Among Patients With Epilepsy At Hospital Kuala Lumpur
حسب: Mastura , Ahmad
منشور في: (2014)

Evaluation Of Doctor’s Knowledge, Attitude, Adherence To Clinical Practice Guideline (Gina 2011) Recommendations And Cost Associated With Asthma Treatment
حسب: Aftab, Raja Ahsan
منشور في: (2014)