Osteoclast-specific marker nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1 expression in stage III giant cell tumor of the bone

Introduction: Osteoclastic bone resorption and osteolysis with tendency for local recurrence and pulmonary metastases are a common complication of stage III Campanacci giant cell tumour of the bone (GCTB). Studies have shown RANKL highly stimulates osteoclastogenesis through nuclear factor of act...

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