Influence of tert gene expression, telomerase activity and telomere length in relation to imatinib mesylate resistance in Malaysian chronic myeloid leukaemia patients

Chronic myeloid leukaemia (CML) is a myeloproliferative neoplasm diagnosed by the presence of the BCR-ABL fusion gene which produces a tyrosine kinase to signal a proliferation of white blood cells. The introduction of imatinib mesylate in early 2000, has dramatically increased the survival of af...

وصف كامل

التفاصيل البيبلوغرافية
المؤلف الرئيسي:	Shamshudin, Wati @ Hayati Mohd
التنسيق:	أطروحة
اللغة:	الإنجليزية
منشور في:	2020
الموضوعات:	R Medicine
الوصول للمادة أونلاين:	http://eprints.usm.my/49320/

مواد مشابهة

Determination of gene copy number status in tert and terc among chronic myeloid leukaemia patients resist ant and responsive to imatinib mesylate treatment
حسب: Asrari, Zaidatul Shakila Mohamad
منشور في: (2014)

Genetic determinants excluding GBCR::ABL mutations of imatinib mesylate therapy response among chronic myeloid leukaemia patients in Malaysia
حسب: Ismail, Siti Mariam
منشور في: (2023)

Molecular genetic and epigenetic mechanisms of primary and secondary resistance to imatinib mesylate treatment in ph chromosome positive chronic myeloid leukemia patients
حسب: Elias, Marjanu Hikmah
منشور في: (2015)

Detection of PDGFRA mutations at exons 12 and 18 among chronic myeloid leukemia patients treated with imatinib mesylate
حسب: Razali, Ruzi Hamimi
منشور في: (2015)

Effects of nicotinamide and nilotinib on telomerase activity and telomere length associated with parp-1 regulation in k562 myeloid cell line
حسب: Muhammad, Nur Rasyidah
منشور في: (2023)

Influence of ORM1, PXR, CAR, CYP3A4 and CYP3A5 gene polymorphisms in mediating susceptibility risk to chronic myeloid leukaemia and response to imatinib mesylate therapy
حسب: Maddin, Najlaa
منشور في: (2017)

Identification of differentially expressed proteins as biomarkers of acute myeloid leukaemia
حسب: Barantalab, Fatemeh
منشور في: (2014)

Regulation Of Telomerase Reverse Transcriptase (Tert) By The Leukaemic Fusion Gene Aml1/Eto
حسب: Moses, Emmanuel Jairaj
منشور في: (2015)

Influences of different phytobiotic supplementations on growth performance, health performance and telomere length expression of broiler chickens
حسب: Abu Kassim, Nafeesa
منشور في: (2022)

Deciphering S-Phase Protein Kinase 2 (Skp2) Mediated Regulation Of Telomerase Reverse Transcriptase (Tert) In Kasumi-1, T (8;21) Acute Myeloid Leukemia (Aml) Cell Line
حسب: Rosli, Nur Aliaa Arina
منشور في: (2023)

Application of high resolution melting (HRM) analysis in detection of PDGFRA gene mutations among chronic myeloid leukemia patients treated with imanitib mesylate
حسب: Rashid, Nur Sabrina Abd
منشور في: (2020)

Gene Expression Profile And Modulation Of Genetic Pathways In Acute Myeloid Leukaemia T(8;21)
حسب: Bashanfer, Salem Ali Alsalem
منشور في: (2013)

Evaluating a rapid method to quantify multiple gene expression in acute myeloid leukaemia
حسب: Lee, Cin Dee
منشور في: (2013)

Expression of survival and apoptotic molecules in response to early stage chemotherapy in acute myeloid leukaemia
حسب: Yiau, Stephnie Kang Xian
منشور في: (2013)

Ultra-high performance liquid chromatography (uhplc) method development and validation for the determination of serum imatinib and its active metabolite concentration among chronic myeloid leukemia patients
حسب: Liong, Tan Ka
منشور في: (2013)

Survival rate and prognostic factors of survival among chronic myeloid leukaemia adults after initiation of tyrosine kinase inhibitor therapy in Hospital Ampang, Selangor
حسب: Ali, Zakiah Bakar
منشور في: (2024)

Non-viral transfection of bone marrow-derived mesenchymal stem cell with human interferon-gamma gene and in vitro efficiency against chronic myeloid leukaemia cells
حسب: Liew, Lee Chuen
منشور في: (2013)

Telomere length and regulatory genes diversity as novel well-being biomarkers in broiler chickens (Gallus gallus domesticus Linnaeus)
حسب: Badmus, Kazeem Ajasa
منشور في: (2021)

Efficacy of dendritic cell-based vaccine on acute myeloid leukaemia in a murine model
حسب: Ng, Wei Yi
منشور في: (2013)

Cockle shell-derived nano carrier for Ara-C in the treatment of acute myeloid leukaemia
حسب: Ghaji, Mustafa Saddam
منشور في: (2018)

Utilization of chemotherapy regimen for acute myeloid leukaemia patients in Ampang Hospital / Jamaliah Jamari
حسب: Jamari, Jamaliah
منشور في: (2015)

Utilization of Chemotherapy Regimen for acute Myeloid Leukaemia Patients in Ampang Hospital / Jamaliah Jamari
حسب: Jamari, Jamaliah
منشور في: (2015)

Expression of potential stem cell-related markers in acute myeloid leukaemia cell lines and gene silencing effect of HOXA3 in THP-1 cells
حسب: Panneerselvan, Hindhuja
منشور في: (2021)

FLT3, NPM1, DNMT3a and NRAS genes mutation in acute myeloid leukaemia in HUSM
حسب: Mat Yunus, Noraini
منشور في: (2015)

The Clinical Significance Of Npm1, Flt3 And Cebpa Gene Mutations In Adult Patients With Acute Myeloid Leukaemia
حسب: Ul Haq, Izaz
منشور في: (2020)

Cytogenomic profiling of chronic lymphocytic leukaemia patients using dna microarray
حسب: Zamri, Wan Norizzati Wan Mohamad
منشور في: (2021)

Microarray-based genomic analysis identifies germline and somatic copy number variants and loss of heterozygosity in acute myeloid leukaemia
حسب: Ambayya @ Ampiah, A Angeli
منشور في: (2015)

Prognostic Markers Of Resistance And Relapse In Acute Leukaemia
حسب: Pon, Maha Abdullah@Maha-Lakswmi
منشور في: (2003)

Generation, Phenotyping and Functional Analysis of Dendritic Cells (DC) Derived from Human Monocytes and Acute Myeloid Leukaemia (AML) Cells
حسب: Lim, Moon Nian
منشور في: (2004)

Effect of consumption of bee products on telomere lenght and longevity of life in beekeepers
حسب: Mohamad Nasir, Nurul Fatihah
منشور في: (2015)

Expression distribution of cancer stem cell, epithelial to mesenchymal transition and telomerase activity in breast cancer and their association with clinicopathological characteristic
حسب: Jaafar Sadeq Makki
منشور في: (2014)

Expression distribution of cancer stem cell, epithelial to mesenchymal transition and telomerase activity in breast cancer, and their association with clinicopathological characteristic
حسب: Jaafar Sadeq Makki
منشور في: (2014)

Pervaporation separation of methyl tert-butyl ether
حسب: Jusoh @ Alias, Nor Zamiha
منشور في: (2009)

Effect of apigenin and cisplatin on telomerase activity and expression of its structural proteins in triple negative breast cancer / Noorfaiza A.Aziz
حسب: A.Aziz, Noorfaiza
منشور في: (2016)

TERF2 gene expression in childhood acute lymphoblastic leukaemia / Lelamekala Vengidasan
حسب: Vengidasan, Lelamekala
منشور في: (2011)

Molecular analysis of survival motor neuron (SMN) and neuronal apoptosis inhibitory protein (NAIP) genes in spinal muscular atrophy (SMA) patients in Malaysia [RJ482.A83 W333 2008 f rb].
حسب: Mohd Shamshudin, Wati @ Hayati
منشور في: (2007)

The effect of resistance heating to the length expansion of cold bending spring steel bar
حسب: Suhaimin, Mohd Khairul Nizam
منشور في: (2020)

Detection of leukaemia-associated aberrant immunophenotype (LAIPs) in acute leukaemia and its association with haematological parameters and treatment outcome
حسب: Rahman, Noor Shaidatul Akmal Ab
منشور في: (2017)

Interpenetrating polymer network natural rubber membranes for separation of methyl tert-buthyl ether and methanol
حسب: Ramlee, Nur Azrini
منشور في: (2009)

Blended chitosan and poly(vinyl alcohol) membranes for the pervaporation of methanol and methyl tert-butyl ether
حسب: Mohd. Sakri, Norhaslina
منشور في: (2009)