Comparison of different subanaesthetic ketamine doses on perioperative opioid consumption in major gynaecological surgery

Background: Ketamine, an N-methyl-D-aspartate (NMDA) receptor antagonist, at a subanaesthetic dose (lower dose), has been used preemptively as an adjuvant to analgesic treatment. In majority of studies, the effective intraoperative bolus doses used are from 0.15 mg/kg to 0.5 mg/kg and infusions in t...

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