Rational Drug Design Of New Folic Acid Analogues With High Binding Affinity And Anticancer Activity
The goal of this thesis is to design new FA analogues with higher selectivity to bind with FRα. Fifty FA-analogues with variant heterocyclic rings were designed and studied for their interaction with FRα. Docking results showed 20 out of the 50 FA-analogues showed higher binding affinity than methot...
| मुख्य लेखक: | Althiabat, Mohammad Gasem Mohammad |
|---|---|
| स्वरूप: | थीसिस |
| भाषा: | अंग्रेज़ी |
| प्रकाशित: |
2020
|
| विषय: | |
| ऑनलाइन पहुंच: | http://eprints.usm.my/53495/ |
| Abstract | Abstract here |
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समान संसाधन
-
Derivatization And Conjugation Of Folic Acid To Improve Its Affinity Towards Folate Receptor Alpha On Cancerous Membrane Bilayer: An In Silico Insight
द्वारा: Althiabat, Mohammad Gasem Mohammad
प्रकाशित: (2024) -
In Silico Study And Synthesis Of Folic Acid-isoniazid Complex As A
Potential Antituberculosis Agent
द्वारा: Tazizi, Mohammad Hafizie Dianel Mohd
प्रकाशित: (2024) -
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द्वारा: Poudel, Arjun
प्रकाशित: (2010) -
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द्वारा: Malik, Madeeha
प्रकाशित: (2013) -
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Analgesic Activity Of Mitragynine
Analogues
द्वारा: Ramlee, Nurul Izzati
प्रकाशित: (2015)