Behavioural, Biochemical, Proteomics Studies And Replacement Therapy Of Morphine And Mitragynine Withdrawal Rat Models
The current study was designed to test the ability of mitragynine to attenuate behavioural signs of morphine-withdrawal in a rat model in comparison to methadone and buprenorphine. A six-day treatment with escalating dose of morphine (10-50 mg/kg, i.p.) induced profound withdrawal signs for 16 days.
| 第一著者: | |
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| フォーマット: | 学位論文 |
| 言語: | 英語 |
| 出版事項: |
2021
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| 主題: | |
| オンライン･アクセス: | http://eprints.usm.my/53633/ |
| 要約: | The current study was designed to test the ability of mitragynine to attenuate behavioural signs of morphine-withdrawal in a rat model in comparison to methadone and buprenorphine. A six-day treatment with escalating dose of morphine (10-50 mg/kg, i.p.) induced profound withdrawal signs for 16 days. |
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