Characterisation of beta globin gene cluster deletions using multiplex-Gap-PCR and Multiplex Ligation-dependent Probe Amplification (MLPA)
Deletions in the beta (β)-globin gene cluster are usually rare, yet this type of mutation is problematic to detect, and subsequently possess a challenge in the diagnostic laboratory. Deletions in this cluster are usually related to the heterozygous of the delta beta thalassaemia (δβ-thalassaemia)...
| Auteur principal: | |
|---|---|
| Format: | Thèse |
| Langue: | anglais |
| Publié: |
2018
|
| Sujets: | |
| Accès en ligne: | http://eprints.usm.my/56770/ |