Mechanism Of Action Of A Benzimidazole Sirtuin Inhibitor, Bzd9l1, In Colorectal Cancer
Sirtuins (SIRTs) are NAD+-dependent deacetylases that is implicated in various epigenetic diseases including cardiovascular and neurodegenerative diseases, diabetes, aging and cancer. The emergence of SIRTs as therapeutic targets and limitations of existing SIRT inhibitors led to the discovery of a...
| Auteur principal: | Tan, Yi Jer |
|---|---|
| Format: | Thèse |
| Langue: | anglais |
| Publié: |
2022
|
| Sujets: | |
| Accès en ligne: | http://eprints.usm.my/59354/ |
| Abstract | Abstract here |
Documents similaires
Evaluation Of Toxicity, Pharmacokinetic And Clastogenicity Profile Of Ethyl 2-[4[(Piperidin-1-yl)
Phenyl]-1h-benzimidazole-5-carboxylate (Bzd9l1), Novel Sirtuin Inhibitor
par: Lee, Yeuan Ting
Publié: (2022)
par: Lee, Yeuan Ting
Publié: (2022)
Bzd9l1: Elucidation Of Its Anti-angiogenic Potential In In-vitro And In-vivo Colorectal Cancer Models
par: Subramaniam, Ayappa V.
Publié: (2023)
par: Subramaniam, Ayappa V.
Publié: (2023)
A Novel Inhibitor Of Sirtuin: Elucidation Of Mode Of Action And Molecular Pathway In Colorectal Cancer Cell Line
par: Tan, Yi Jer
Publié: (2017)
par: Tan, Yi Jer
Publié: (2017)
Synthesis And Biological Activity Of Benzimidazole Analogs As Sirtuin Enzyme Inhibitors
par: Yeong, Keng Yoon
Publié: (2016)
par: Yeong, Keng Yoon
Publié: (2016)
Crispr/Cas9-Mediated Suppression Of Dual-Specificity Phosphatase 6 (Dusp6) Inhibits Cell Viability, Growth, Survival And Adhesion In Ht-29 Human Colorectal Cancer Cell Line
par: Ahmad, Muhammad Khairi
Publié: (2024)
par: Ahmad, Muhammad Khairi
Publié: (2024)
A Hospital-based Case-control Study of Factors
Associated with Colorectal Cancer
par: Rosdi, Aminu Aisyahtun
Publié: (2016)
par: Rosdi, Aminu Aisyahtun
Publié: (2016)
Clinicopathological Analysis And Mrna Expression Profiling Of G1/S Phase Cyclins And Cdk4 In Formalin Fixed Paraffin Embedded Colorectal Cancer Tissue
par: Gururuloo, Sarminiyy Lenga
Publié: (2024)
par: Gururuloo, Sarminiyy Lenga
Publié: (2024)
Elucidation Of Circular Rna (Circ007667 And Circ037236) Roles In Colorectal Cancer Pathogenesis
par: Wang, Fang
Publié: (2024)
par: Wang, Fang
Publié: (2024)
Pharmacological Potential Of Moringa Oleifera Silver Nanoparticles Targeting Angiogenesis And Colorectal Cancer Cell Lines Inhibition
par: Al-Shalabi, Rolla Ziyad Mustafa
Publié: (2025)
par: Al-Shalabi, Rolla Ziyad Mustafa
Publié: (2025)
Genetic Polymorphisms Of Inflammation Response Genes And Their Influence On Malaysian Colorectal Cancer Patients : A Case Control Study
par: Mustapha, Mohd Aminudin
Publié: (2012)
par: Mustapha, Mohd Aminudin
Publié: (2012)
Combinatorial Crispr/Cas9 For Suppression Of Latent Hiv-1 Provirus In Vitro
par: Ravichantar, Nithya
Publié: (2020)
par: Ravichantar, Nithya
Publié: (2020)
Elucidating The In Vitro Antiproliferative Properties And Associated Mechanisms Of Momordica
Cochinchinensis Spreng (Gac Fruit) Aqueous Extract Using Colorectal Cancer Origin Cell Lines
par: Thavamany, Priscilla Jayanthi
Publié: (2024)
par: Thavamany, Priscilla Jayanthi
Publié: (2024)
Tubulin-Targeting Activity Of Phytoestrogens Present In Cosmos Caudatus Aqueous Extract Against Colorectal Cancer Cell Line Ht-29
par: Xu, Fan
Publié: (2023)
par: Xu, Fan
Publié: (2023)
Benzimidazole derivatives as potential dual inhibitors for poly (adp-ribose) polymerase-1 and dihydroorotate
dehydrogenase / Iskandar Abdullah
par: Iskandar, Abdullah
Publié: (2015)
par: Iskandar, Abdullah
Publié: (2015)
Exploring the landscape of common actionable molecular markers in colorectal cancer / Li Jing
par: Li, Jing
Publié: (2019)
par: Li, Jing
Publié: (2019)
Identification Of Antimalarial Compounds And Their Mode Of Actions
par: Mahmud, Fauze
Publié: (2022)
par: Mahmud, Fauze
Publié: (2022)
Synthesis, docking and biological activity : a novel series of benzimidazole derivatives as potential neuraminidase inhibitors
par: Nurasyikin Hamzah
Publié: (2024)
par: Nurasyikin Hamzah
Publié: (2024)
Mechanism Of Actions Of Bilimbi Fractions And Its Natural Compounds In Stimulating Brown Adipocyte Differentiation
par: Fauzi, Farah Binti Md
Publié: (2024)
par: Fauzi, Farah Binti Md
Publié: (2024)
Physico-Chemical Characterisation Of Mangrove Tannins As Corrosion Inhibitors
par: Rahim, Afidah Abdul
Publié: (2005)
par: Rahim, Afidah Abdul
Publié: (2005)
Elucidating Lysosomal Autophagy Mechanism in LRG1-Mediated Colorectal Cancer
par: Lim Su Min (P103436)
Publié: (2023)
par: Lim Su Min (P103436)
Publié: (2023)
Phosphorylation Of Human Interferon Regulatory Factor 9 During Type I Interferon Response
par: Anak Paul Joko, Alvin Dickson
Publié: (2021)
par: Anak Paul Joko, Alvin Dickson
Publié: (2021)
Characterisation of transcription factor binding site on the promoter of MIF and CSE1L that are involved in colorectal cancer
par: Intan Fairuz Ramli
Publié: (2023)
par: Intan Fairuz Ramli
Publié: (2023)
Virtual High Throughput Screening For Avian
Influenza (H5nl) Neuraminidase Inhibitors
par: Ismail, Nurul Izza
Publié: (2011)
par: Ismail, Nurul Izza
Publié: (2011)
The synthesis and characterization of the novel Carbonic anhydrase IX (CA IX) inhibitor against breast and colorectal cancer
par: Zhou, XiaoQun
Publié: (2026)
par: Zhou, XiaoQun
Publié: (2026)
Validation of PASD1 protein as an immunotherapeutic target in colorectal cancer
par: Joanne Soh Ern Chi
Publié: (2023)
par: Joanne Soh Ern Chi
Publié: (2023)
The Effect Of Ethanolic Bee Pollen Extract From Geniotrigona Thoracica On Dna Damage And Dna Methylation In Ht-29 Colorectal Cell Line
par: Harif Fadzilah, Nurdianah
Publié: (2022)
par: Harif Fadzilah, Nurdianah
Publié: (2022)
In Vitro And In Vivo Effects Of Bisphenol A On Cell Growth, Lipid Accumulation And Inflammation In Liver Cell Line, Rat Adipose And Colorectal Tissues
par: Ismael, Ismael Layla Qasim
Publié: (2024)
par: Ismael, Ismael Layla Qasim
Publié: (2024)
Correction Of Glucose-6-Phosphate Dehydrogenase (G6PD) Viangchan Mutation In Monocytes Using CRISPR/CAS9
par: Vengidasan, Lelamekala
Publié: (2018)
par: Vengidasan, Lelamekala
Publié: (2018)
Inhibitory Effects Of Andrographolide In Pc-3 Cell Line And The Induction Of Apoptosis Via The Involvement Of Caspases 3, 8 And 9
par: Manimaran, Janany
Publié: (2023)
par: Manimaran, Janany
Publié: (2023)
Determination Of Mitragynine As A Substrate, Inducer, Or Inhibitor Of P-Glycoprotein Drug Transporter, And Prediction Of Drug-Herb Interaction Risks
par: Rusli, Noradliyanti
Publié: (2017)
par: Rusli, Noradliyanti
Publié: (2017)
Genomic Expression Profile Of Human Papillomavirus 16 And 18 – Associated Pre-cancerous Lesions And Cancer Of The Cervix
par: Balasubramaniam, Shandra Devi
Publié: (2022)
par: Balasubramaniam, Shandra Devi
Publié: (2022)
Determination Of Prognostic Markers For Cervical Cancer
par: Ahmad, Rahmatul Wahida
Publié: (2008)
par: Ahmad, Rahmatul Wahida
Publié: (2008)
The Role Of Rarβ Gene On Cancer Stemness Capability In
Non-Small Cell Lung Cancer Cell Line
par: Abu Halim, Noor Hanis
Publié: (2024)
par: Abu Halim, Noor Hanis
Publié: (2024)
Elucidation Of The Role Of Long Noncoding Rna Kcnma1-As2 In Colorectal Cancer
par: Miao, Xinzhi
Publié: (2024)
par: Miao, Xinzhi
Publié: (2024)
The Effects of Channa Striatus
Extract Administration on Wound
Healing Markers (il-6, Mmp-9 and Vegf)
in Post Lower Segment Caesarean
Section (lscs) Women
par: Zainan, Ahmad Ezam
Publié: (2016)
par: Zainan, Ahmad Ezam
Publié: (2016)
Posttraumatic Growth And
Psychosocial, Cancer And Treatment
Related Factors In Head And Neck Cancer: Assessing Their Associations In A Cross-Sectional Study
par: Hamdan, Nur Amirah
Publié: (2022)
par: Hamdan, Nur Amirah
Publié: (2022)
Posttraumatic Growth And Psychosocial, Cancer And Treatment
Related Factors In Head And Neck Cancer: Assessing Their Associations In A Cross-Sectional Study
par: Hamdan, Nur Amirah
Publié: (2022)
par: Hamdan, Nur Amirah
Publié: (2022)
Investigation On Cancer Chemopreventive Activity Of Fabricated Tq Encapsulated Plga-Pf68 Nanoparticles On Selected Breast Cancer Cell Lines
par: Noor, Nurul Shahfiza
Publié: (2022)
par: Noor, Nurul Shahfiza
Publié: (2022)
Matrix Metalloproteinase -9 and Tissue Inhibitors of Metalloproteinasr-1 and -2 as Potential Novel Biomakers in Gestational Hypertension
par: Ab Hamid, Jabrullah
Publié: (2010)
par: Ab Hamid, Jabrullah
Publié: (2010)
Thiazolidinediones Pretreated Bone Marrow-Derived Mesenchymal Stem Cells As An Anti-Cancer Approach Against Mcf-7 Breast Cancer Cell Line
par: Lim, Shern Kwok
Publié: (2022)
par: Lim, Shern Kwok
Publié: (2022)
Documents similaires
-
Evaluation Of Toxicity, Pharmacokinetic And Clastogenicity Profile Of Ethyl 2-[4[(Piperidin-1-yl)
Phenyl]-1h-benzimidazole-5-carboxylate (Bzd9l1), Novel Sirtuin Inhibitor
par: Lee, Yeuan Ting
Publié: (2022) -
Bzd9l1: Elucidation Of Its Anti-angiogenic Potential In In-vitro And In-vivo Colorectal Cancer Models
par: Subramaniam, Ayappa V.
Publié: (2023) -
A Novel Inhibitor Of Sirtuin: Elucidation Of Mode Of Action And Molecular Pathway In Colorectal Cancer Cell Line
par: Tan, Yi Jer
Publié: (2017) -
Synthesis And Biological Activity Of Benzimidazole Analogs As Sirtuin Enzyme Inhibitors
par: Yeong, Keng Yoon
Publié: (2016) -
Crispr/Cas9-Mediated Suppression Of Dual-Specificity Phosphatase 6 (Dusp6) Inhibits Cell Viability, Growth, Survival And Adhesion In Ht-29 Human Colorectal Cancer Cell Line
par: Ahmad, Muhammad Khairi
Publié: (2024)
