Mechanism Of Action Of A Benzimidazole Sirtuin Inhibitor, Bzd9l1, In Colorectal Cancer
Sirtuins (SIRTs) are NAD+-dependent deacetylases that is implicated in various epigenetic diseases including cardiovascular and neurodegenerative diseases, diabetes, aging and cancer. The emergence of SIRTs as therapeutic targets and limitations of existing SIRT inhibitors led to the discovery of a...
| Main Author: | Tan, Yi Jer |
|---|---|
| Format: | Thesis |
| Language: | English |
| Published: |
2022
|
| Subjects: | |
| Online Access: | http://eprints.usm.my/59354/ |
| Abstract | Abstract here |
Similar Items
Evaluation Of Toxicity, Pharmacokinetic And Clastogenicity Profile Of Ethyl 2-[4[(Piperidin-1-yl)
Phenyl]-1h-benzimidazole-5-carboxylate (Bzd9l1), Novel Sirtuin Inhibitor
by: Lee, Yeuan Ting
Published: (2022)
by: Lee, Yeuan Ting
Published: (2022)
A Novel Inhibitor Of Sirtuin: Elucidation Of Mode Of Action And Molecular Pathway In Colorectal Cancer Cell Line
by: Tan, Yi Jer
Published: (2017)
by: Tan, Yi Jer
Published: (2017)
Bzd9l1: Elucidation Of Its Anti-angiogenic Potential In In-vitro And In-vivo Colorectal Cancer Models
by: Subramaniam, Ayappa V.
Published: (2023)
by: Subramaniam, Ayappa V.
Published: (2023)
Synthesis And Biological Activity Of Benzimidazole Analogs As Sirtuin Enzyme Inhibitors
by: Yeong, Keng Yoon
Published: (2016)
by: Yeong, Keng Yoon
Published: (2016)
Crispr/Cas9-Mediated Suppression Of Dual-Specificity Phosphatase 6 (Dusp6) Inhibits Cell Viability, Growth, Survival And Adhesion In Ht-29 Human Colorectal Cancer Cell Line
by: Ahmad, Muhammad Khairi
Published: (2024)
by: Ahmad, Muhammad Khairi
Published: (2024)
A Hospital-based Case-control Study of Factors
Associated with Colorectal Cancer
by: Rosdi, Aminu Aisyahtun
Published: (2016)
by: Rosdi, Aminu Aisyahtun
Published: (2016)
Clinicopathological Analysis And Mrna Expression Profiling Of G1/S Phase Cyclins And Cdk4 In Formalin Fixed Paraffin Embedded Colorectal Cancer Tissue
by: Gururuloo, Sarminiyy Lenga
Published: (2024)
by: Gururuloo, Sarminiyy Lenga
Published: (2024)
Genetic Polymorphisms Of Inflammation Response Genes And Their Influence On Malaysian Colorectal Cancer Patients : A Case Control Study
by: Mustapha, Mohd Aminudin
Published: (2012)
by: Mustapha, Mohd Aminudin
Published: (2012)
Combinatorial Crispr/Cas9 For Suppression Of Latent Hiv-1 Provirus In Vitro
by: Ravichantar, Nithya
Published: (2020)
by: Ravichantar, Nithya
Published: (2020)
Elucidating The In Vitro Antiproliferative Properties And Associated Mechanisms Of Momordica
Cochinchinensis Spreng (Gac Fruit) Aqueous Extract Using Colorectal Cancer Origin Cell Lines
by: Thavamany, Priscilla Jayanthi
Published: (2024)
by: Thavamany, Priscilla Jayanthi
Published: (2024)
Tubulin-Targeting Activity Of Phytoestrogens Present In Cosmos Caudatus Aqueous Extract Against Colorectal Cancer Cell Line Ht-29
by: Xu, Fan
Published: (2023)
by: Xu, Fan
Published: (2023)
Identification Of Antimalarial Compounds And Their Mode Of Actions
by: Mahmud, Fauze
Published: (2022)
by: Mahmud, Fauze
Published: (2022)
Elucidation Of The Role Of Long Noncoding Rna Kcnma1-As2 In Colorectal Cancer
by: Miao, Xinzhi
Published: (2024)
by: Miao, Xinzhi
Published: (2024)
Anti-Cancer Studies Of Garcinia Mangostana L. And Syzygium Campanulatum Korth Towards Colorectal Carcinoma
by: Aisha, Abdalrahim F. A.
Published: (2011)
by: Aisha, Abdalrahim F. A.
Published: (2011)
Physico-Chemical Characterisation Of Mangrove Tannins As Corrosion Inhibitors
by: Rahim, Afidah Abdul
Published: (2005)
by: Rahim, Afidah Abdul
Published: (2005)
Modulation of purine metabolism and apoptotic pathway via ENT2 CRISPR/Cas9 knockout in colorectal cancer cell lines / Safaa Mahmoud Naes
by: Mahmoud Naes, Safaa
Published: (2022)
by: Mahmoud Naes, Safaa
Published: (2022)
Phosphorylation Of Human Interferon Regulatory Factor 9 During Type I Interferon Response
by: Anak Paul Joko, Alvin Dickson
Published: (2021)
by: Anak Paul Joko, Alvin Dickson
Published: (2021)
Genotoxicity Assessment Of Standardised Root Extract Of Eurycoma Longifolia Jack And Synthesis Of Some Benzimidazole Derivatives And Evaluation Of Their Anti-Cancer Potential
by: Muttiah, Nithya Niranjini
Published: (2013)
by: Muttiah, Nithya Niranjini
Published: (2013)
Identification Of Biomarkers For Colorectal
Cancer From Malaysian Patients
by: Yeoh , Lay Chin
Published: (2010)
by: Yeoh , Lay Chin
Published: (2010)
Identification Of Biomarkers For Colorectal Cancer From Malaysian Patients
by: Yeoh, Lay Chin
Published: (2010)
by: Yeoh, Lay Chin
Published: (2010)
Comparison Of Protein Expression Between Breast And Colorectal Cancers
by: Lee , Hui Hua
Published: (2012)
by: Lee , Hui Hua
Published: (2012)
Virtual High Throughput Screening For Avian
Influenza (H5nl) Neuraminidase Inhibitors
by: Ismail, Nurul Izza
Published: (2011)
by: Ismail, Nurul Izza
Published: (2011)
Pharmacokinetics And Metabolism Studies
Of Antifilarial Drugs
Derivatives Of Benzimidazole Carbamate
by: Ramanathan, Surash
Published: (1996)
by: Ramanathan, Surash
Published: (1996)
Synthesis, Characterization And Anti-Proliferation Study Of Some Benzimidazole Derivatives
by: al-Douh, Mohammed Hadi Saeed
Published: (2010)
by: al-Douh, Mohammed Hadi Saeed
Published: (2010)
The Effect Of Ethanolic Bee Pollen Extract From Geniotrigona Thoracica On Dna Damage And Dna Methylation In Ht-29 Colorectal Cell Line
by: Harif Fadzilah, Nurdianah
Published: (2022)
by: Harif Fadzilah, Nurdianah
Published: (2022)
In Vitro And In Vivo Effects Of Bisphenol A On Cell Growth, Lipid Accumulation And Inflammation In Liver Cell Line, Rat Adipose And Colorectal Tissues
by: Ismael, Ismael Layla Qasim
Published: (2024)
by: Ismael, Ismael Layla Qasim
Published: (2024)
Correction Of Glucose-6-Phosphate Dehydrogenase (G6PD) Viangchan Mutation In Monocytes Using CRISPR/CAS9
by: Vengidasan, Lelamekala
Published: (2018)
by: Vengidasan, Lelamekala
Published: (2018)
Inhibitory Effects Of Andrographolide In Pc-3 Cell Line And The Induction Of Apoptosis Via The Involvement Of Caspases 3, 8 And 9
by: Manimaran, Janany
Published: (2023)
by: Manimaran, Janany
Published: (2023)
Cytotoxicity of methanol and aqueous Lignosus rhinoceros (Tiger Milk mushroom) extracts on HCT 116 human colorectal cancer cells and its mode of action / Suziana Zaila Hj Che Fauzi
by: Hj Che Fauzi, Suziana Zaila
Published: (2016)
by: Hj Che Fauzi, Suziana Zaila
Published: (2016)
Mechanistic Studies Of The Anticancer Activity Of The Extract Of Eupatorium Odoratum L. And Euphorbia Hirta L
by: Harun, Faizah
Published: (2012)
by: Harun, Faizah
Published: (2012)
Determination Of Mitragynine As A Substrate, Inducer, Or Inhibitor Of P-Glycoprotein Drug Transporter, And Prediction Of Drug-Herb Interaction Risks
by: Rusli, Noradliyanti
Published: (2017)
by: Rusli, Noradliyanti
Published: (2017)
Genomic Expression Profile Of Human Papillomavirus 16 And 18 – Associated Pre-cancerous Lesions And Cancer Of The Cervix
by: Balasubramaniam, Shandra Devi
Published: (2022)
by: Balasubramaniam, Shandra Devi
Published: (2022)
The Role Of Fdg Pet-Ct In Detection Of Recurrent Colorectal Cancer In National Cancer Institute, Putrajaya, Malaysia
by: Wong, Teck Huat
Published: (2016)
by: Wong, Teck Huat
Published: (2016)
Determination Of Prognostic Markers For Cervical Cancer
by: Ahmad, Rahmatul Wahida
Published: (2008)
by: Ahmad, Rahmatul Wahida
Published: (2008)
The Role Of Rarβ Gene On Cancer Stemness Capability In
Non-Small Cell Lung Cancer Cell Line
by: Abu Halim, Noor Hanis
Published: (2024)
by: Abu Halim, Noor Hanis
Published: (2024)
Cytotoxic Activity And Mechanisms Of Action Of Crinum Asiaticum Extracts On Various Cancer Cell Lines
by: Mohd Yusoff, Sa'adiah
Published: (2017)
by: Mohd Yusoff, Sa'adiah
Published: (2017)
Investigating the expression of soluble pd-l1 (spd-l1) of breast cancer patients using elisa in Hospital USM, Kelantan
by: Anwar, Nur Amira Khairil
Published: (2024)
by: Anwar, Nur Amira Khairil
Published: (2024)
The Effects of Channa Striatus
Extract Administration on Wound
Healing Markers (il-6, Mmp-9 and Vegf)
in Post Lower Segment Caesarean
Section (lscs) Women
by: Zainan, Ahmad Ezam
Published: (2016)
by: Zainan, Ahmad Ezam
Published: (2016)
Posttraumatic Growth And
Psychosocial, Cancer And Treatment
Related Factors In Head And Neck Cancer: Assessing Their Associations In A Cross-Sectional Study
by: Hamdan, Nur Amirah
Published: (2022)
by: Hamdan, Nur Amirah
Published: (2022)
Posttraumatic Growth And Psychosocial, Cancer And Treatment
Related Factors In Head And Neck Cancer: Assessing Their Associations In A Cross-Sectional Study
by: Hamdan, Nur Amirah
Published: (2022)
by: Hamdan, Nur Amirah
Published: (2022)
Similar Items
-
Evaluation Of Toxicity, Pharmacokinetic And Clastogenicity Profile Of Ethyl 2-[4[(Piperidin-1-yl)
Phenyl]-1h-benzimidazole-5-carboxylate (Bzd9l1), Novel Sirtuin Inhibitor
by: Lee, Yeuan Ting
Published: (2022) -
A Novel Inhibitor Of Sirtuin: Elucidation Of Mode Of Action And Molecular Pathway In Colorectal Cancer Cell Line
by: Tan, Yi Jer
Published: (2017) -
Bzd9l1: Elucidation Of Its Anti-angiogenic Potential In In-vitro And In-vivo Colorectal Cancer Models
by: Subramaniam, Ayappa V.
Published: (2023) -
Synthesis And Biological Activity Of Benzimidazole Analogs As Sirtuin Enzyme Inhibitors
by: Yeong, Keng Yoon
Published: (2016) -
Crispr/Cas9-Mediated Suppression Of Dual-Specificity Phosphatase 6 (Dusp6) Inhibits Cell Viability, Growth, Survival And Adhesion In Ht-29 Human Colorectal Cancer Cell Line
by: Ahmad, Muhammad Khairi
Published: (2024)