Pharmacokinetics And Pharmacodynamics Modeling Of Clozapine In Healthy Volunteers And Patients With Schizophrenia Spectrum Disorders Using Pharmacometrics Approach

Clozapine is the first-line medication for treatment-resistant schizophrenia. However, it has complex metabolism, an unclear exposure-response relationship, and potential adverse drug reactions (ADRs). The present study aimed to develop an analytical method and pharmacometrics-based models for cloza...

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Détails bibliographiques
Auteur principal:	Orwa, Albitar
Format:	Thèse
Langue:	anglais
Publié:	2022
Sujets:	RS1-441 Pharmacy and materia medica
Accès en ligne:	http://eprints.usm.my/59662/
Abstract	Abstract here

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