An in vitro study of stereoselectivity of cytochrome p450 enzymes in the metabolism of 3,4-methylenedioxymethamphetamine
Cytochrome P450 (CYP) enzymes metabolise 3,4- methylenedioxymethamphetamine (MDMA). MDMA is a neurotoxic drug of abuse with stimulant and hallucinogenic properties. Its metabolism is stereoselective with (S)-MDMA preferred over (fl)-MDMA. Since MDMA stereoisomers possess different pharmacokineti...
| Main Author: | |
|---|---|
| Format: | Thesis |
| Language: | English |
| Published: |
2013
|
| Subjects: | |
| Online Access: | http://eprints.usm.my/60902/ |