Molecular analysis of the promoter and the core promoter region Of the smn2 gene in circumscribing the clinical severity of sma
Spinal muscular atrophy (SMA) is a neurodegenerative disorder caused by the absence of the full length SMN protein (FL-SMN) as a result of mutation or deletion of SMN\ gene. The isoform to this gene, SMN2, with mutation in 1 base pair, encodes for 10% of FL-SMN protein and is reported to decrease...
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| Format: | Thèse |
| Langue: | anglais |
| Publié: |
2012
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| Accès en ligne: | http://eprints.usm.my/60940/ |