Rapid eye movement sleep deprivation induces vascular endothelial dysfunction in rats: roles of oxidative stress-mediated nitric oxide signalling and vitamin c supplementation

Rapid eye movement (REM) sleep deprivation (REMsd) is associated with oxidative stress, the primary factor in the mechanism of endothelial dysfunction. Endothelial dysfunction has been attributed to a reduction in nitric oxide (NO.) bioavailability. To date, the mechanism of endothelial dysfunction...

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