| Summary: | The incidence of hyperglycaemia, hypertension and hyperlipidaemia (3Hs)
have been prevalent in many developed and developing countries. Sacha Inchi oil (SIO) is a rich source of plant-based omega-3, 6, and 9 polyunsaturated fatty acids with promising health effects. However, the effects of SIO as complementary medicine among the 3Hs individuals are narrowly investigated. The present randomised, doubleblind, placebo-controlled human clinical trial aimed to explore the effects of SIO supplementation on (1) glycaemic control; (2) BPs; (3) lipid profiles; (4) inflammatory
status; (5) oxidative stress; (6) circulating arterial calcification biomarkers; (7)
anthropometry measurements; (8) quality of life; (9) mental health status; and (10)
compliancy and tolerability among 3Hs patients. Fifty-four (n=54) 3Hs patients were recruited from Specialist Day Care Clinic, Pusat Perubatan USM Bertam, and
randomised into two groups: the SIO group (n=27) (received 1000mg of SIO soft gel per day) or placebo group (n=27) (received 1000mg corn oil soft gel for 12 weeks).
Fasting blood samples were collected at baseline and post week-12 to assess clinical and laboratory biochemical markers.
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