Design, Synthesis, Molecular Docking And Cytotoxic Activity Of New Ortho-Hydroxy Chalcone And Pyrazoline Derivatives

This study focused on the design and synthesis of new compounds with anticancer activity. The compounds were constructed using the structure-based drug design, focusing on their binding capabilities to the Colchicine (PDB code: IS AO) active site in a bidentate manner, with the most energetically...

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