Development Of Dna Aptamer Against Envelope 2 Protein Of Chikungunya Virus And Their Diagnostic Potentiality
Chikungunya virus (CHIKV) infections are mosquito-borne viral infections that are always underreported and misdiagnosed as other virus infections. Antigen detection tests can detect CHIKV in acute-phase samples but are beleaguered by issues associated with antibodies that are sensitive to temperatur...
| Main Author: | |
|---|---|
| Format: | Thesis |
| Language: | English |
| Published: |
2024
|
| Subjects: | |
| Online Access: | http://eprints.usm.my/63009/ |
| Abstract | Abstract here |
| _version_ | 1855630538896834560 |
|---|---|
| author | Andrew, Anna |
| author_facet | Andrew, Anna |
| author_sort | Andrew, Anna |
| description | Chikungunya virus (CHIKV) infections are mosquito-borne viral infections that are always underreported and misdiagnosed as other virus infections. Antigen detection tests can detect CHIKV in acute-phase samples but are beleaguered by issues associated with antibodies that are sensitive to temperatures, expensive and prone to batch variations. As an alternative to antibodies, aptamers are cheaper and have no batch-to-batch variation. This study aims to isolate aptamers that can be used to develop diagnostic tests for CHIKV |
| first_indexed | 2025-10-17T08:54:57Z |
| format | Thesis |
| id | usm-63009 |
| institution | Universiti Sains Malaysia |
| language | English |
| last_indexed | 2025-10-17T08:54:57Z |
| publishDate | 2024 |
| record_format | EPrints |
| record_pdf | Restricted |
| spelling | usm-630092025-10-17T03:14:09Z http://eprints.usm.my/63009/ Development Of Dna Aptamer Against Envelope 2 Protein Of Chikungunya Virus And Their Diagnostic Potentiality Andrew, Anna R5-920 Medicine (General) Chikungunya virus (CHIKV) infections are mosquito-borne viral infections that are always underreported and misdiagnosed as other virus infections. Antigen detection tests can detect CHIKV in acute-phase samples but are beleaguered by issues associated with antibodies that are sensitive to temperatures, expensive and prone to batch variations. As an alternative to antibodies, aptamers are cheaper and have no batch-to-batch variation. This study aims to isolate aptamers that can be used to develop diagnostic tests for CHIKV 2024-01 Thesis NonPeerReviewed application/pdf en http://eprints.usm.my/63009/1/Pages%20from%20ANNA%20ANDREW%20-%20TESIS.pdf Andrew, Anna (2024) Development Of Dna Aptamer Against Envelope 2 Protein Of Chikungunya Virus And Their Diagnostic Potentiality. PhD thesis, Universiti Sains Malaysia. |
| spellingShingle | R5-920 Medicine (General) Andrew, Anna Development Of Dna Aptamer Against Envelope 2 Protein Of Chikungunya Virus And Their Diagnostic Potentiality |
| thesis_level | PhD |
| title | Development Of Dna Aptamer Against Envelope 2 Protein Of Chikungunya Virus And Their Diagnostic Potentiality |
| title_full | Development Of Dna Aptamer Against Envelope 2 Protein Of Chikungunya Virus And Their Diagnostic Potentiality |
| title_fullStr | Development Of Dna Aptamer Against Envelope 2 Protein Of Chikungunya Virus And Their Diagnostic Potentiality |
| title_full_unstemmed | Development Of Dna Aptamer Against Envelope 2 Protein Of Chikungunya Virus And Their Diagnostic Potentiality |
| title_short | Development Of Dna Aptamer Against Envelope 2 Protein Of Chikungunya Virus And Their Diagnostic Potentiality |
| title_sort | development of dna aptamer against envelope 2 protein of chikungunya virus and their diagnostic potentiality |
| topic | R5-920 Medicine (General) |
| url | http://eprints.usm.my/63009/ |
| work_keys_str_mv | AT andrewanna developmentofdnaaptameragainstenvelope2proteinofchikungunyavirusandtheirdiagnosticpotentiality |