| Summary: | Benign prostatic hyperplasia (BPH) is becoming increasingly prevalent, and
although transurethral resection of the prostate (TURP) remains the standard surgical
treatment, late postoperative urethral stricture remains a potential complication. This
cross-sectional study aimed to identify risk factors for urethral stricture following
TURP. Clinical data from 400 BPH patients (mean age, 74.31 ± 6.70 years) who
underwent TURP at Chengdu University Affiliated Hospital between June 2020 and
June 2023 were retrospectively analyzed. This study divided the data into two groups:
the urethral stricture group and the non-urethral stricture group. All data were
analyzed using univariate and multivariate logistic regression analysis (P < 0.05 was
set as the significance criterion). A total of 35 patients (8.75%) developed urethral
stricture. Multivariate analysis identified age (OR = 1.121, 95% CI: 1.044–1.204, P =
0.002), prostate size (OR = 1.038, 95% CI: 1.014–1.062, P = 0.002), preoperative
indwelling catheter (OR = 5.413, 95% CI: 1.872 – 15.655, P = 0.002), and
postoperative indwelling catheter time (OR = 2.147, 95% CI: 1.405–3.280, P < 0.001)
as independent risk factors for urethral stricture, whereas preoperative urethral
dilation (OR = 0.049, 95% CI: 0.011–0.220, P < 0.001) was an independent
protective factor. The nomogram prediction model established based on the above
independent influencing factors (AUC = 0.916) has good application prospects in
clinical diagnosis and risk assessment
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